Preparation and characterization of nanosilver-doped porous hydroxyapatite scaffolds

被引：33

作者：

Zhou, Kui ^{[1
]}

Dong, Chunfa ^{[1
,2
]}

Zhang, Xianglin ^{[1
]}

Shi, Lei ^{[1
]}

Chen, Zhichao ^{[1
]}

Xu, Yanlin ^{[1
]}

Cai, Hao ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Sch Mat Sci & Engn, State Key Lab Mat Proc & Die & Mould Technol, Wuhan 430074, Peoples R China

[2] Hubei Polytechn Univ, Sch Mech & Elect Engn, Huangshi 435003, Peoples R China

来源：

CERAMICS INTERNATIONAL | 2015年 / 41卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Silver nanoparticles; Hydroxyapatite; Porous scaffold; Antibacterial activity; ONE-STEP SYNTHESIS; SILVER NANOPARTICLES; ANTIBACTERIAL ACTIVITY; GOLD NANOPARTICLES; FABRICATION; COMPOSITE; COATINGS; SIZE;

D O I：

10.1016/j.ceramint.2014.09.108

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Silver nanoparticle (Ag-np) is a new kind of antibacterial agent which is widely used in medical supplies. In this study, a simple approach is described to obtain Ag-doped HA scaffolds. Hydroxyapatite (HA) bone scaffolds with controllable pore size were fabricated by a micro-syringe extrusion system. Sintered HA scaffolds were then immersed in silver reaction hydrosol in order to get Ag-doped HA scaffolds. SEM and EDS shows a uniform distribution of silver nanoparticles on the surface of HA scaffolds. Such Ag-np doped HA scaffolds, displaying a good antibacterial activity against Escherichia coli (E. coli), are likely to prevent bone implant associated bacterial infections. (C) 2014 Elsevier Ltd and Techna Group S.r.l. All rights reserved.

引用

页码：1671 / 1676

页数：6

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