Preparation and characterization of nanosilver-doped porous hydroxyapatite scaffolds

被引：33
|
作者：
Zhou, Kui [1 ]
Dong, Chunfa [1 ,2 ]
Zhang, Xianglin [1 ]
Shi, Lei [1 ]
Chen, Zhichao [1 ]
Xu, Yanlin [1 ]
Cai, Hao [1 ]
机构：
[1] Huazhong Univ Sci & Technol, Sch Mat Sci & Engn, State Key Lab Mat Proc & Die & Mould Technol, Wuhan 430074, Peoples R China
[2] Hubei Polytechn Univ, Sch Mech & Elect Engn, Huangshi 435003, Peoples R China
来源：
CERAMICS INTERNATIONAL | 2015年 / 41卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Silver nanoparticles; Hydroxyapatite; Porous scaffold; Antibacterial activity; ONE-STEP SYNTHESIS; SILVER NANOPARTICLES; ANTIBACTERIAL ACTIVITY; GOLD NANOPARTICLES; FABRICATION; COMPOSITE; COATINGS; SIZE;
D O I：
10.1016/j.ceramint.2014.09.108
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Silver nanoparticle (Ag-np) is a new kind of antibacterial agent which is widely used in medical supplies. In this study, a simple approach is described to obtain Ag-doped HA scaffolds. Hydroxyapatite (HA) bone scaffolds with controllable pore size were fabricated by a micro-syringe extrusion system. Sintered HA scaffolds were then immersed in silver reaction hydrosol in order to get Ag-doped HA scaffolds. SEM and EDS shows a uniform distribution of silver nanoparticles on the surface of HA scaffolds. Such Ag-np doped HA scaffolds, displaying a good antibacterial activity against Escherichia coli (E. coli), are likely to prevent bone implant associated bacterial infections. (C) 2014 Elsevier Ltd and Techna Group S.r.l. All rights reserved.
引用
收藏
页码：1671 / 1676
页数：6
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