Methods and Challenges in Quantitative Imaging Biomarker Development

被引：69
|
作者：
Abramson, Richard G. [1 ]
Burton, Kirsteen R. [2 ,3 ]
Yu, John-Paul J. [4 ]
Scalzetti, Ernest M. [5 ]
Yankee, Thomas E. [6 ]
Rosenkrantz, Andrew B. [7 ]
Mendiratta-Lala, Mishal [8 ]
Barth, Brian J. [9 ]
Ganeshan, Dhakshinamoorthy [10 ]
Lenchik, Leon [11 ]
Subramaniam, Rathan M. [12 ,13 ]
机构：
[1] Vanderbilt Univ, Dept Radiol & Radiol Sci, Nashville, TN 37232 USA
[2] Univ Toronto, Dept Med Imaging, Toronto, ON, Canada
[3] Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada
[4] Univ Calif San Francisco, Dept Radiol & Biomed Imaging, San Francisco, CA 94143 USA
[5] SUNY Upstate Med Univ, Dept Radiol, Syracuse, NY 13210 USA
[6] Vanderbilt Univ, Inst Imaging Sci, Nashville, TN 37232 USA
[7] NYU, Dept Radiol, Langone Med Ctr, New York, NY 10016 USA
[8] Henry Ford Hosp, Abdominal & Cross Sect Intervent Radiol, Detroit, MI 48202 USA
[9] Mayo Clin, Div Radiol Informat, Rochester, MN USA
[10] Univ Texas MD Anderson Canc Ctr, Dept Abdominal Imaging, Houston, TX 77030 USA
[11] Wake Forest Sch Med, Dept Radiol, Winston Salem, NC USA
[12] Johns Hopkins Sch Med, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD USA
[13] Johns Hopkins Univ, Dept Hlth Policy & Management, Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD 21218 USA
来源：
ACADEMIC RADIOLOGY | 2015年 / 22卷 / 01期
基金：
美国医疗保健研究与质量局; 美国国家卫生研究院;
关键词：
Radiology; quantitative imaging; biomarker development; CONTRAST-ENHANCED MRI; CLINICAL-TRIAL DESIGNS; TUMOR RESPONSE; BREAST-CANCER; MURINE MODEL; REPRODUCIBILITY; VALIDATION; RADIOLOGY; CHEMOTHERAPY; MICROPET;
D O I：
10.1016/j.acra.2014.09.001
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Academic radiology is poised to play an important role in the development and implementation of quantitative imaging (QI) tools. This article, drafted by the-Association of University Radiologists Radiology Research Alliance Quantitative Imaging Task Force, reviews current issues in QI biomarker research. We discuss motivations for advancing QI, define key terms, present a framework for QI biomarker research, and outline challenges in QI biomarker development. We conclude by describing where QI research and development is currently taking place and discussing the paramount role of academic radiology in this rapidly evolving field.
引用
收藏
页码：25 / 32
页数：8
相关论文
共 50 条
  • [21] Quantitative methods for molecular ultrasound imaging
    Sadeghipour, Negar
    Tabesh, Farbod
    Natarajan, Arutselvan
    Jones, Meredith A.
    Chen, Xuxin
    Paulmurugan, Ramasamy
    Zheng, Bin
    El Kaffas, Ahmed
    MEDICAL IMAGING 2023, 2023, 12470
  • [22] Editorial: Quantitative bone imaging methods
    Salmon, Phil
    Alavi, Fatemeh
    Ghasem-Zadeh, Ali
    FRONTIERS IN ENDOCRINOLOGY, 2024, 15
  • [23] Navigating challenges and solutions in quantitative photoacoustic imaging
    Zhang, Ruochong
    A'dawiah, Rabia'tul
    Choo, Tristan Wen Jie
    Li, Xiuting
    Balasundaram, Ghayathri
    Qi, Yi
    Goh, Yonggeng
    Bi, Renzhe
    Olivo, Malini
    APPLIED PHYSICS REVIEWS, 2024, 11 (03):
  • [24] QUANTITATIVE METHODS IN MANAGEMENT DEVELOPMENT
    KEARNEY, WJ
    MARTIN, DD
    BUSINESS HORIZONS, 1974, 17 (04) : 51 - 57
  • [25] Quantitative Imaging Biomarker Ontology (QIBO) for Knowledge Representation of Biomedical Imaging Biomarkers
    Buckler, Andrew J.
    Ouellette, M.
    Danagoulian, J.
    Wernsing, G.
    Liu, Tiffany Ting
    Savig, Erica
    Suzek, Baris E.
    Rubin, Daniel L.
    Paik, David
    JOURNAL OF DIGITAL IMAGING, 2013, 26 (04) : 630 - 641
  • [26] Quantitative Imaging Biomarker Ontology (QIBO) for Knowledge Representation of Biomedical Imaging Biomarkers
    Andrew J. Buckler
    M. Ouellette
    J. Danagoulian
    G. Wernsing
    Tiffany Ting Liu
    Erica Savig
    Baris E. Suzek
    Daniel L. Rubin
    David Paik
    Journal of Digital Imaging, 2013, 26 : 630 - 641
  • [27] Challenges in Communicating and Understanding Predictive Biomarker Imaging for Alzheimer Disease
    Chiong, Winston
    JAMA NEUROLOGY, 2018, 75 (01) : 18 - 19
  • [28] Ethical Challenges in Biomarker-Driven Drug Development
    Hey, Spencer Phillips
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2018, 103 (01) : 23 - 25
  • [29] Imaging biomarker applications in oncology drug development
    Miller, Janet C.
    Pien, Homer H.
    Sorensen, A. Gregory
    DRUG INFORMATION JOURNAL, 2007, 41 (05): : 561 - 572
  • [30] Imaging Biomarker Applications in Oncology Drug Development
    Janet C. Miller
    Homer H. Pien
    A. Gregory Sorensen
    Drug information journal : DIJ / Drug Information Association, 2007, 41 : 561 - 572
12345