Synthesis of novel 1,3-dioxolane nucleoside analogues

被引：0
|
作者：
Cai, DM
Lin, KH
Li, MZ
Wen, JW
Li, HY
You, TP [1 ]
机构：
[1] Univ Sci & Technol China, Dept Chem, Anhua 230026, Peoples R China
[2] Shanghai Univ, Dept Chem, Shanghai 200436, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2004年 / 22卷 / 12期
关键词：
nucleoside; 1,3-dioxolane; tiazofurin; ribavirin; imidazole;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Novel 1,3-dioxolane C-nucleoside analogues of tiazofurin 2-(2-hydroxymethyl-1,3-dioxolan-4-yl)-1,3-thiazole-4-carboxamide as well as N-nucleoside analogues of substituted imidazoles 1-(2-hydroxymethyl-1,3-dioxolan-4-yl)-4-nitroimidazole and 1-(2-hydroxymethyl-1,3-dioxolan-4-yl)-4,5-dicyanoimidazole were synthesized from methyl acrylate through a multistep procedure. Their structures were confirmed by IR, H-1 NMR, C-13 NMR spectra and elemental analysis.
引用
收藏
页码：1425 / 1431
页数：7
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