Synthesis of novel 1,3-dioxolane nucleoside analogues

被引：0
|
作者：
Cai, DM
Lin, KH
Li, MZ
Wen, JW
Li, HY
You, TP [1 ]
机构：
[1] Univ Sci & Technol China, Dept Chem, Anhua 230026, Peoples R China
[2] Shanghai Univ, Dept Chem, Shanghai 200436, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2004年 / 22卷 / 12期
关键词：
nucleoside; 1,3-dioxolane; tiazofurin; ribavirin; imidazole;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Novel 1,3-dioxolane C-nucleoside analogues of tiazofurin 2-(2-hydroxymethyl-1,3-dioxolan-4-yl)-1,3-thiazole-4-carboxamide as well as N-nucleoside analogues of substituted imidazoles 1-(2-hydroxymethyl-1,3-dioxolan-4-yl)-4-nitroimidazole and 1-(2-hydroxymethyl-1,3-dioxolan-4-yl)-4,5-dicyanoimidazole were synthesized from methyl acrylate through a multistep procedure. Their structures were confirmed by IR, H-1 NMR, C-13 NMR spectra and elemental analysis.
引用
收藏
页码：1425 / 1431
页数：7
相关论文
共 50 条
  • [31] RADICAL TELOMERIZATION OF ETHYLENE WITH 1,3-DIOXOLANE
    NAYANOV, VP
    ZORIN, VV
    ZLOTSKII, SS
    TERENTEV, AB
    RAKHMANKULOV, DL
    JOURNAL OF APPLIED CHEMISTRY OF THE USSR, 1976, 48 (12): : 2863 - 2865
  • [32] CATIONIC COPOLYMERIZATION OF 1,3-DIOXOLANE WITH STYRENE
    OKADA, M
    YAMASHIT.Y
    ISHII, Y
    INTERNATIONAL CHEMICAL ENGINEERING, 1966, 6 (01): : 163 - &
  • [33] STUDIES ON COPOLYMERIZATION OF TRIOXANE AND 1,3-DIOXOLANE
    OPITZ, G
    ZEITSCHRIFT FUR CHEMIE, 1971, 11 (08): : 313 - &
  • [34] Synthesis and Solution Self-Assembly of Poly(1,3-dioxolane)
    Qiu, Huan
    Yang, Zhening
    Koehler, Moritz
    Ling, Jun
    Schacher, Felix H.
    MACROMOLECULES, 2019, 52 (09) : 3359 - 3366
  • [35] Synthesis of 1,3-Dioxolane Derivatives from β-Chlorolactic Acid and Ketones
    A. S. Shevchuk
    V. A. Podgornova
    B. F. Ustavshchikov
    Russian Journal of Organic Chemistry, 2001, 37 : 704 - 706
  • [36] CATIONIC COPOLYMERIZATION OF TRIOXANE AND 1,3-DIOXOLANE
    JAACKS, V
    ADVANCES IN CHEMISTRY SERIES, 1969, (91): : 371 - &
  • [37] COPOLYMERIZATION BY CRYSTALLIZATION OF TRIOXANE WITH 1,3-DIOXOLANE
    MORELLI, F
    BACCARED.M
    GIORGINI, M
    LUCCHESI, A
    TARTAREL.R
    EUROPEAN POLYMER JOURNAL, 1970, 6 (06) : 891 - &
  • [38] CATIONIC COPOLYMERIZATION OF 1,3-DIOXOLANE WITH STYRENE
    OKADA, M
    YAMASHITA, Y
    ISHII, Y
    MAKROMOLEKULARE CHEMIE, 1966, 94 (JUN): : 181 - +
  • [39] Synthesis of N-1-oxypyrimidine 1,3-dioxolane and 1,3-oxathiolane nucleosides
    Nguyen-Be, N
    Lee, N
    Chan, L
    Zacharie, B
    CHEMICAL COMMUNICATIONS, 2000, (23) : 2311 - 2312
  • [40] HOMOLYTIC ADDITION OF 1,3-DIOXOLANE TO PYRIDINE
    BORISOVA, IA
    ZORIN, VV
    ZLOTSKII, SS
    RAKHMANKULOV, DL
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1979, (07): : 990 - 991
12345