Synthesis of benzonaphtho[1,4]diazepine derivatives via the reaction of 2-aminoarylbenzimidamides with 2,3-dichloro-1,4-naphthoquinone

被引：13
|
作者：
El-Shaieb, Kamal M. [1 ]
机构：
[1] Menia Univ, Dept Chem, Fac Sci, El Minia, Egypt
来源：
JOURNAL OF CHEMICAL RESEARCH | 2010年 / 03期
关键词：
aminobenzimidamides; naphthoquinone; CT-complexes; benzonaphthodiazepines; BIOLOGICAL EVALUATION; ANTIPLATELET; INHIBITORS; AFFINITY;
D O I：
10.3184/030823410X12659615450519
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A series of (Z)-13-(arylimino)-12,13-dihydro-5H-benzo[e]naphtho[2,3-b][1,4]diazepine-6,11-dione derivatives have been synthesised by one pot cyclisation in good yield via electron donor-acceptor complexes by reacting 2-amino-arylbenzimidamides with 2,3-dichloro-1,4-naphthoquinone. The high yield and simplified workup procedure in addition to the mild and neutral reaction conditions are the main advantages of this approach.
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页码：137 / 139
页数：3
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