Synthesis of benzonaphtho[1,4]diazepine derivatives via the reaction of 2-aminoarylbenzimidamides with 2,3-dichloro-1,4-naphthoquinone

被引:13
|
作者
El-Shaieb, Kamal M. [1 ]
机构
[1] Menia Univ, Dept Chem, Fac Sci, El Minia, Egypt
关键词
aminobenzimidamides; naphthoquinone; CT-complexes; benzonaphthodiazepines; BIOLOGICAL EVALUATION; ANTIPLATELET; INHIBITORS; AFFINITY;
D O I
10.3184/030823410X12659615450519
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of (Z)-13-(arylimino)-12,13-dihydro-5H-benzo[e]naphtho[2,3-b][1,4]diazepine-6,11-dione derivatives have been synthesised by one pot cyclisation in good yield via electron donor-acceptor complexes by reacting 2-amino-arylbenzimidamides with 2,3-dichloro-1,4-naphthoquinone. The high yield and simplified workup procedure in addition to the mild and neutral reaction conditions are the main advantages of this approach.
引用
收藏
页码:137 / 139
页数:3
相关论文
共 50 条
  • [31] MECHANISM OF BASE CATALYSED CONDENSATION OF NAPHTHOLS WITH 2,3-DICHLORO-1,4-NAPHTHOQUINONE
    SAEVA, FD
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1971, (NSEP): : 57 - &
  • [32] EDA complexes of 2,3-dichloro-1,4-naphthoquinone with some substituted anilines
    Neelgund, GM
    Kulkarni, AS
    Budni, ML
    MONATSHEFTE FUR CHEMIE, 2004, 135 (04): : 343 - 355
  • [33] SPECTROPHOTOMETRIC DETERMINATION OF 4-ACETYLAMINOBENZALDEHYDE THIOSEMICARBAZONE (THIACETAZONE) WITH 2,3-DICHLORO-1,4-NAPHTHOQUINONE
    SHISHOO, CJ
    DEVANI, MB
    SHAH, MG
    ANALYST, 1973, 98 (1171) : 762 - 765
  • [34] Reaction of 2,3-dichloro-1,4-naphthoquinone with some active methylene compounds in different basic media
    Hammam A.S.
    Fandy R.F.
    Hassan M.A.
    Chemistry of Heterocyclic Compounds, 2002, 38 (04) : 400 - 405
  • [35] Reaction of 2,3-dichloro-1,4-naphthoquinone with some active methylene compounds indifferent basic media
    Hammam, AS
    Fandy, RF
    Hassan, MA
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2002, (04): : 465 - 470
  • [36] CRYSTAL AND MOLECULAR-STRUCTURE OF AN ORTHORHOMBIC MODIFICATION OF 2,3-DICHLORO-1,4-NAPHTHOQUINONE
    IKEMOTO, I
    YAKUSHI, K
    NAITO, Y
    KURODA, H
    SANO, M
    ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1977, 33 (JUL15): : 2076 - 2079
  • [37] Reactions of 2,3-dichloro-1,4-naphthoquinone with piperidine, amine and some thiol nucleophile
    Patan, Abubaker
    Goksel, F. Serpil
    Ayla, Sibel Sahinler
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2021, 196 (07) : 647 - 655
  • [38] Reaction of enamines of the 1,2,3,4-tetrahydrobenzo[f]isoquinoline series with 2,3-Dichloro-1,4-naphthoquinone
    Polygalova N.N.
    Mikhailovskii A.G.
    Gein V.L.
    Vakhrin M.I.
    Chemistry of Heterocyclic Compounds, 2005, 41 (2) : 258 - 259
  • [39] Reaction of enamines in the series of 1,2,3,4-tetrahydrobenzo[f]isoquinoline with 2,3-dichloro-1,4-naphthoquinone
    Polygalova, NN
    Mikhailovskii, AG
    Gein, VL
    Vakhrin, MI
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 2005, (02): : 291 - 292
  • [40] INVOLVEMENT OF SUPEROXIDE IN THE INTERACTION OF 2,3-DICHLORO-1,4-NAPHTHOQUINONE WITH MITOCHONDRIAL-MEMBRANES
    PRITSOS, CA
    JENSEN, DE
    PISANI, D
    PARDINI, RS
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1982, 217 (01) : 98 - 109