Bis(cyclopentadienyl)zirconium dichloride for alkylation of heteroaromatics and synthesis of bis(indolyl)methanes

被引：0
|
作者：
Kantam, ML [1 ]
Aziz, K [1 ]
Likhar, PR [1 ]
机构：
[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India
来源：
CATALYSIS LETTERS | 2004年 / 98卷 / 2-3期
关键词：
bis(cyclopentadienyl) zirconium dichloride; epoxide; indoles; bis-(indolyl)methane;
D O I：
10.1007/s10562-004-7925-5
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Bis(cyclopentadienyl)zirconium dichloride catalyzed alkylation of heteroaromatics with epoxides results in the formation of 3-alkylated heteroaromatics in high yields. Cp2ZrCl2 is also found to be an efficient catalyst for the electrophilic substitution reaction of indoles with aldehydes and ketones to afford the corresponding bis(indolyl)methanes in high yields with complete regioselectivity.
引用
收藏
页码：117 / 121
页数：5
相关论文
共 50 条
  • [31] Synthesis of bis(indolyl)methanes catalyzed by surface modified zirconia
    Nadkarni, Sharmin V.
    Gawande, Manoj B.
    Jayaram, Radha V.
    Nagarkar, Jayashree M.
    CATALYSIS COMMUNICATIONS, 2008, 9 (08) : 1728 - 1733
  • [32] Eutectic salts promote green synthesis of bis(indolyl) methanes
    Azizi, Najmadin
    Manocheri, Zohreh
    RESEARCH ON CHEMICAL INTERMEDIATES, 2012, 38 (07) : 1495 - 1500
  • [33] Synthesis, antimicrobial and antioxidant evaluation of quinolines and bis(indolyl)methanes
    Praveen, C.
    DheenKumar, P.
    Muralidharan, D.
    Perumal, P. T.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (24) : 7292 - 7296
  • [34] A convenient synthesis of bis(indolyl)methanes catalyzed by diphosphooctadecatungstic acid
    Heravi, Majid M.
    Bakhtiari, Khadijeh
    Fatehi, Azadeh
    Bamoharram, Fatemeh F.
    CATALYSIS COMMUNICATIONS, 2008, 9 (02) : 289 - 292
  • [35] Eutectic salts promote green synthesis of bis(indolyl) methanes
    Najmadin Azizi
    Zohreh Manocheri
    Research on Chemical Intermediates, 2012, 38 : 1495 - 1500
  • [36] BIS(CYCLOPENTADIENYL)ZIRCONIUM
    WATT, GW
    DRUMMOND, FO
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1966, 88 (24) : 5926 - &
  • [37] A practical synthesis of bis(indolyl)methanes employing boric acid
    Yadav, Jhillu S.
    Gupta, Manoj K.
    Jain, Ruchi
    Yadav, Nagendra N.
    Reddy, Basi V. Subba
    MONATSHEFTE FUR CHEMIE, 2010, 141 (09): : 1001 - 1004
  • [38] A practical synthesis of bis(indolyl)methanes employing boric acid
    Jhillu S. Yadav
    Manoj K. Gupta
    Ruchi Jain
    Nagendra N. Yadav
    Basi V. Subba Reddy
    Monatshefte für Chemie - Chemical Monthly, 2010, 141 : 1001 - 1004
  • [39] Synthesis of Bis(indolyl)methanes Catalyzed by Cyclic Phosphoric Acid
    He, Lin
    Wang, Xiangbo
    Du, Guangfen
    Dai, Bin
    Jian, Tengyue
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2013, 33 (05) : 988 - 994
  • [40] Organocatalytic Combinatorial Synthesis of Quinazoline, Quinoxaline and Bis(indolyl)methanes
    Malamiri, Fatemeh
    Khaksar, Samad
    Badri, Rashid
    Tahanpesar, Elham
    COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2020, 23 (01) : 83 - 88
12345