Bis(cyclopentadienyl)zirconium dichloride for alkylation of heteroaromatics and synthesis of bis(indolyl)methanes

被引：0

作者：

Kantam, ML ^{[1
]}

Aziz, K ^{[1
]}

Likhar, PR ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India

来源：

CATALYSIS LETTERS | 2004年 / 98卷 / 2-3期

关键词：

bis(cyclopentadienyl) zirconium dichloride; epoxide; indoles; bis-(indolyl)methane;

D O I：

10.1007/s10562-004-7925-5

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Bis(cyclopentadienyl)zirconium dichloride catalyzed alkylation of heteroaromatics with epoxides results in the formation of 3-alkylated heteroaromatics in high yields. Cp2ZrCl2 is also found to be an efficient catalyst for the electrophilic substitution reaction of indoles with aldehydes and ketones to afford the corresponding bis(indolyl)methanes in high yields with complete regioselectivity.

引用

页码：117 / 121

页数：5

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