An Aldehyde-Azomethine Imine [3+2]-Cycloaddition: High-Yielding Regioselective Synthesis of Substituted N,N-Bicyclic Pyrazolidinones

被引：5
|
作者：
Gujral, Jagjeet [1 ]
Reddy, T. Prabhakar [1 ]
Gorachand, B. [1 ]
Ramachary, Dhevalapally B. [1 ]
机构：
[1] Univ Hyderabad, Sch Chem, Catalysis Lab, Hyderabad 500046, India
来源：
CHEMISTRYSELECT | 2018年 / 3卷 / 27期
关键词：
acetaldehydes; azomethine imines; N; N-bicyclic pyrazolidinones; click reaction; 3+2]-cycloaddition; 1,3-DIPOLAR CYCLOADDITION REACTION; AZIDE-ALKYNE CYCLOADDITION; METAL-FREE SYNTHESIS; CLICK CHEMISTRY; DIRECT ACCESS; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; AZIDOPHENYL ARYLSELENIDES; STEREOSELECTIVE-SYNTHESIS; ORGANOCATALYTIC SYNTHESIS; REGIOSPECIFIC SYNTHESIS;
D O I：
10.1002/slct.201801328
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An enolate mediated aldehyde-azomethine imine [3+2] cycloaddition of various aldehydes with N,N-cyclic azomethine imines is reported under DBU or tBuOK-catalysis. High reaction rate, ease of operation, simple catalyst, easily accessible starting materials and a wide substrate scope with numerous applications make this reaction an ideal addition to the click chemistry.
引用
收藏
页码：7900 / 7905
页数：6
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