An Aldehyde-Azomethine Imine [3+2]-Cycloaddition: High-Yielding Regioselective Synthesis of Substituted N,N-Bicyclic Pyrazolidinones

被引：5

作者：

Gujral, Jagjeet ^{[1
]}

Reddy, T. Prabhakar ^{[1
]}

Gorachand, B. ^{[1
]}

Ramachary, Dhevalapally B. ^{[1
]}

机构：

[1] Univ Hyderabad, Sch Chem, Catalysis Lab, Hyderabad 500046, India

来源：

CHEMISTRYSELECT | 2018年 / 3卷 / 27期

关键词：

acetaldehydes; azomethine imines; N; N-bicyclic pyrazolidinones; click reaction; 3+2]-cycloaddition; 1,3-DIPOLAR CYCLOADDITION REACTION; AZIDE-ALKYNE CYCLOADDITION; METAL-FREE SYNTHESIS; CLICK CHEMISTRY; DIRECT ACCESS; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; AZIDOPHENYL ARYLSELENIDES; STEREOSELECTIVE-SYNTHESIS; ORGANOCATALYTIC SYNTHESIS; REGIOSPECIFIC SYNTHESIS;

D O I：

10.1002/slct.201801328

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An enolate mediated aldehyde-azomethine imine [3+2] cycloaddition of various aldehydes with N,N-cyclic azomethine imines is reported under DBU or tBuOK-catalysis. High reaction rate, ease of operation, simple catalyst, easily accessible starting materials and a wide substrate scope with numerous applications make this reaction an ideal addition to the click chemistry.

引用

页码：7900 / 7905

页数：6

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