Fluorescence "on-off-on" chemosensor for selective detection of Hg2+ and S2-: application to bioimaging in living cells

被引：64

作者：

Vengaian, K. Muthu ^{[1
]}

Britto, C. Denzil ^{[1
]}

Sekar, Karuppannan ^{[1
]}

Sivaraman, Gandhi ^{[2
]}

Singaravadivel, Subramanian ^{[3
]}

机构：

[1] Anna Univ, Univ Coll Engn, Dept Chem, Dindigul 624622, India

[2] Inst Stem Cell Biol & Regenerat Med, Bangalore 560065, Karnataka, India

[3] SSM Inst Engn & Technol, Dept Chem, Dindigul 624002, India

来源：

RSC ADVANCES | 2016年 / 6卷 / 09期

关键词：

AQUEOUS-MEDIA; MERCURY IONS; TURN-ON; DERIVATIVES; PROBE; SENSOR; WATER; RECOGNITION; EFFICIENT; FLUORIDE;

D O I：

10.1039/c5ra26281j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A phenothiazine based diamino-malenonitrile-linked chromogenic and fluorogenic probe (P-1) was synthesized and characterized for the specific detection of Hg2+ and S2-. In the presence of Hg2+, the probe produces "switch-off" along with a color change from yellow to brown, allowing colorimetric detection of Hg2+ by the naked eye. The sensitivity of probe P-1 towards Hg2+ and S2- was demonstrated in living cells, and cell toxicity assay also reveals that the probe P-1 can be used for selective imaging of Hg2+ and S2- in living cells.

引用

页码：7668 / 7673

页数：6

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