Fluorescence "on-off-on" chemosensor for selective detection of Hg2+ and S2-: application to bioimaging in living cells

被引：64
|
作者：
Vengaian, K. Muthu [1 ]
Britto, C. Denzil [1 ]
Sekar, Karuppannan [1 ]
Sivaraman, Gandhi [2 ]
Singaravadivel, Subramanian [3 ]
机构：
[1] Anna Univ, Univ Coll Engn, Dept Chem, Dindigul 624622, India
[2] Inst Stem Cell Biol & Regenerat Med, Bangalore 560065, Karnataka, India
[3] SSM Inst Engn & Technol, Dept Chem, Dindigul 624002, India
来源：
RSC ADVANCES | 2016年 / 6卷 / 09期
关键词：
AQUEOUS-MEDIA; MERCURY IONS; TURN-ON; DERIVATIVES; PROBE; SENSOR; WATER; RECOGNITION; EFFICIENT; FLUORIDE;
D O I：
10.1039/c5ra26281j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A phenothiazine based diamino-malenonitrile-linked chromogenic and fluorogenic probe (P-1) was synthesized and characterized for the specific detection of Hg2+ and S2-. In the presence of Hg2+, the probe produces "switch-off" along with a color change from yellow to brown, allowing colorimetric detection of Hg2+ by the naked eye. The sensitivity of probe P-1 towards Hg2+ and S2- was demonstrated in living cells, and cell toxicity assay also reveals that the probe P-1 can be used for selective imaging of Hg2+ and S2- in living cells.
引用
收藏
页码：7668 / 7673
页数：6
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