The effect of a formulation excipient on monoclonal antibody tryptophan oxidation

被引:0
|
作者
Yang, Jessica [1 ]
Strahan, Alex [2 ]
Alavattam, Sreedhara [3 ]
Wang, Y. John [3 ]
Kabakoff, Bruce [1 ]
Salisbury, Cleo [1 ]
机构
[1] Genentech Inc, Early Stage Pharmaceut Dev, San Francisco, CA 94080 USA
[2] Genentech Inc, Prot Analyt Chem, San Francisco, CA 94080 USA
[3] Genentech Inc, Late Stage Pharmaceut Dev, San Francisco, CA 94080 USA
来源
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2018年 / 255卷
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
213
引用
收藏
页数:1
相关论文
共 50 条
  • [41] Interaction between preservatives and a monoclonal antibody in support of multidose formulation development
    Karunaratne, Sachini P.
    Jolliffe, Madeleine C.
    Trayton, Isabelle
    Shanmugam, Ramesh Kumar
    Darton, Nicholas J.
    Weis, David D.
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 648
  • [42] Identification and Characterization of Polysorbate-Degrading Enzymes in a Monoclonal Antibody Formulation
    Graf, Tobias
    Tomlinson, Anthony
    Yuk, Inn H.
    Kufer, Regina
    Spensberger, Bernhard
    Falkenstein, Roberto
    Shen, Amy
    Li, Hong
    Duan, Dana
    Liu, Wenqiang
    Wohlrab, Stefanie
    Edelmann, Franziska
    Leiss, Michael
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 110 (11) : 3558 - 3567
  • [43] The Molecular Chaperone α-Crystallin as an Excipient in an Insulin Formulation
    Rasmussen, Tue
    Tantipolphan, Ruedeeporn
    van de Weert, Marco
    Jiskoot, Wim
    PHARMACEUTICAL RESEARCH, 2010, 27 (07) : 1337 - 1347
  • [44] The effect of glass container surface silanol density on monoclonal antibody formulation stability after application of mechanical shock
    Wang, Junjie
    Guo, Xiang
    Jiang, Xingchun
    Hu, Xueyan
    Wang, Cui
    Han, Yang
    Wu, Hao
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2025, 670
  • [45] The Molecular Chaperone α-Crystallin as an Excipient in an Insulin Formulation
    Tue Rasmussen
    Ruedeeporn Tantipolphan
    Marco van de Weert
    Wim Jiskoot
    Pharmaceutical Research, 2010, 27 : 1337 - 1347
  • [46] Preformulation studies on grewia gum as a formulation excipient
    Nep, Elijah I.
    Conway, Barbara R.
    JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2012, 108 (01) : 197 - 205
  • [47] Formulation Study for Excipient Compositions of Pravastatin Tablet
    Kim, Kang Min
    LATIN AMERICAN JOURNAL OF PHARMACY, 2018, 37 (09): : 1709 - 1717
  • [48] Excipient-excipient interactions in the development of nanocarriers: an innovative statistical approach for formulation decisions
    Beraldo-de-Araujo, Viviane Lucia
    Beraldo-de-Araujo, Anderson
    Ribeiro Costa, Juliana Souza
    Martins Pelegrine, Ana Carolina
    Moraes Ribeiro, Ligia Nunes
    de Paula, Eneida
    Oliveira-Nascimento, Laura
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [49] Preformulation studies on grewia gum as a formulation excipient
    Elijah I. Nep
    Barbara R. Conway
    Journal of Thermal Analysis and Calorimetry, 2012, 108 : 197 - 205
  • [50] CHITOSAN: A NOVEL EXCIPIENT IN PHARMACEUTICAL FORMULATION: A REVIEW
    Singh, Manoj Kumar
    Prajapati, Sunil Kumar
    Mahor, Alok
    Rajput, Neha
    Singh, Raghvendra
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (09): : 2266 - 2277