An efficient synthesis of thiazolo[3,2-a]pyrimidinones

被引：9
|
作者：
Ahmad, Nadia M. [1 ]
Jones, Keith [1 ]
机构：
[1] Inst Canc Res, Canc Res UK Ctr Canc Therapeut, Sutton SM2 5NG, Surrey, England
来源：
TETRAHEDRON LETTERS | 2010年 / 51卷 / 25期
关键词：
4-QUINOLONES; ACCESS; ACID;
D O I：
10.1016/j.tetlet.2010.04.052
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of thiazolo[3,2-a]pyrimidinones was synthesised in a two-step procedure, using Eaton's reagent to effect cyclisation of 2-aminothiazoles. The use of relatively low temperatures, facile product isolation and short reaction times make this cyclisation procedure a particularly attractive option over more conventional methods. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3263 / 3265
页数：3
相关论文
共 50 条
  • [11] SYNTHESIS OF NOVEL BENZOFURO-FUSED THIAZOLO[3,2-a]-PYRIMIDINONES VIA PICTET-SPENGLER REACTION
    Wang, Dao-Lin
    Wang, Dong
    Qiang, Jian-Hua
    Liu, Lin
    HETEROCYCLES, 2016, 92 (03) : 552 - 559
  • [12] New multicomponent synthesis of functionally substituted partially hydrogenated thiazolo[3,2-a]quinoline and thiazolo[3,2-a]pyridine
    Dyachenko, I. V.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2015, 51 (11) : 1584 - 1586
  • [13] New multicomponent synthesis of functionally substituted partially hydrogenated thiazolo[3,2-a]quinoline and thiazolo[3,2-a]pyridine
    I. V. Dyachenko
    Russian Journal of Organic Chemistry, 2015, 51 : 1584 - 1586
  • [14] An efficient method for the synthesis of thieno[30',2':2,3] pyrido-[4,5-d]thiazolo[3,2-a] pyrimidinones
    Wang, Dao-Lin
    Wang, Dong
    Xing, Jin-Juan
    Qian, Jian-Hua
    CHINESE CHEMICAL LETTERS, 2017, 28 (03) : 579 - 582
  • [15] Unequivocal synthesis of substituted thiazolo[3,2-a]benzimidazoles
    Rewcastle, Gordon W.
    ARKIVOC, 2020, : 214 - 227
  • [16] Synthesis of (benzo)thiazolo[3,2-a]pyridine derivatives
    A. V. Shelepyuk
    L. M. Potikha
    V. A. Kovtunenko
    Chemistry of Heterocyclic Compounds, 2013, 49 : 348 - 349
  • [17] A SYNTHESIS OF THIAZOLO[3,2-A]PYRIDINE RING SYSTEM
    BALSIGER, RW
    MONTGOME.JA
    JOHNSTON, TP
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1965, 2 (01) : 97 - &
  • [18] SYNTHESIS OF THIAZOLO[3,2-A]PYRIDINE DERIVATIVES AND THEIR REACTIONS
    MATSUDA, Y
    MATSUMOTO, H
    IDE, S
    FURUNO, K
    TORISU, K
    ITOU, T
    MOTOKAWA, C
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1993, 113 (01): : 32 - 39
  • [19] SYNTHESIS OF "BENZO[G]THIAZOLO[3,2-A]QUINAZOLINES
    GAKHAR, HK
    GUPTA, R
    KUMAR, N
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1977, 15 (12): : 1115 - 1117
  • [20] Synthesis of Novel Thiazolo[3,2-a]pyrimidine Compounds
    Zeng, Rongjin
    Zhou, Zaichun
    Wang, Zhaoxu
    Li, Xiaofang
    Chen, Zhong
    Yu, Xianyong
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2009, 29 (03) : 470 - 475
12345