Efficient and eco-friendly process for the synthesis of bis(1H-indol-3-yl)methanes using ionic liquids

被引：144
|
作者：
Yadav, JS [1 ]
Reddy, BVS [1 ]
Sunitha, S [1 ]
机构：
[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2003年 / 345卷 / 03期
关键词：
aldehydes; bis-indolylmethanes; ionic liquids; ketones;
D O I：
10.1002/adsc.200390038
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Indoles react smoothly with carbonyl compounds in 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4) or 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF6) ionic liquids under mild reaction conditions to afford the corresponding bis-indolylmethanes in excellent yields. These ionic liquids can be recovered and recycled in subsequent reactions without any apparent loss of activity.
引用
收藏
页码：349 / 352
页数：4
相关论文
共 50 条
  • [31] Novel N-Substituted ((1H-indol-3-yl)methylene)benzohydrazides and ((1H-indol-3-yl)methylene)-2-phenylhydrazines: Synthesis and Antiplatelet Aggregation Activity
    Kalhor, Nadia
    Mardani, Matin
    Abdollahzadeh, Sepideh
    Vakof, Mona
    Zadeh, Marjan Esfahani
    Tehrani, Kamaleddin Haj Mohammad Ebrahim
    Kobarfard, Farzad
    Mohebbi, Shohreh
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2015, 36 (11) : 2632 - 2639
  • [32] Synthesis, characterization and the antimicrobial activity of new eco-friendly ionic liquids
    Messali, Mouslim
    Moussa, Ziad
    Alzahrani, Abdullah Y.
    El-Naggar, Moustafa Y.
    ElDouhaibi, Ahmad S.
    Judeh, Zaher M. A.
    Hammouti, Belkheir
    CHEMOSPHERE, 2013, 91 (11) : 1627 - 1634
  • [33] Eco-friendly synthesis and antimicrobial activities of substituted-5-(1H-indol-3-yl)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione derivatives
    Thirupathi, G.
    Venkatanarayana, M.
    Dubey, P. K.
    Kumari, Y. Bharathi
    MEDICINAL CHEMISTRY RESEARCH, 2014, 23 (03) : 1569 - 1580
  • [34] Eco-friendly synthesis and antimicrobial activities of substituted-5-(1H-indol-3-yl)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione derivatives
    G. Thirupathi
    M. Venkatanarayana
    P. K. Dubey
    Y. Bharathi Kumari
    Medicinal Chemistry Research, 2014, 23 : 1569 - 1580
  • [35] Efficient and eco-friendly process for the synthesis of bi(indolyl)methanes catalyzed by sodium hydrogensulfate monohydrate in ionic liquid n-butylpyridinium tetrafluoroborate
    Zhang, Li Ping
    Li, Yi Qun
    Zhou, Mei Yun
    CHINESE CHEMICAL LETTERS, 2006, 17 (06) : 723 - 726
  • [36] Efficient and Eco-friendly Process for the Synthesis of Bi(indolyl)methanes Catalyzed by Sodium Hydrogensulfate Monohydrate in Ionic Liquid n-Butylpyridinium Tetrafluoroborate
    Li Ping ZHANG
    Chinese Chemical Letters, 2006, (06) : 723 - 726
  • [37] Propyl 2-(1H-indol-3-yl)acetate
    Tang, Guo-Min
    Xu, Wei
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O1686 - +
  • [38] 2′-[(5-chloro-1H-indol-3-yl)methylene]2-(1H-indol-3-yl)acetohydrazide
    Ali, Hapipah M.
    Shimar, Jamaludin Nazzatush
    Jefrey, Basirun Wan
    Ng, Seik Weng
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O1807 - O1808
  • [39] (E)-Methyl 3-(1H-indol-3-yl)acrylate
    Li, Dong-Feng
    Zhu, Xiao-Fei
    Guan, Shuang
    Hou, Rui-Bin
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O3290 - U976
  • [40] Synthesis of 4,6-disubstituted-2-(1H-indol-3-yl)-benzothiazoles
    Záletová, J
    Dzurilla, M
    Kutschy, P
    Pazdera, P
    Kovácik, V
    Aldölfi, J
    Bekesová, S
    COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 2004, 69 (02) : 453 - 460
12345