Efficient and eco-friendly process for the synthesis of bis(1H-indol-3-yl)methanes using ionic liquids

被引：144
|
作者：
Yadav, JS [1 ]
Reddy, BVS [1 ]
Sunitha, S [1 ]
机构：
[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2003年 / 345卷 / 03期
关键词：
aldehydes; bis-indolylmethanes; ionic liquids; ketones;
D O I：
10.1002/adsc.200390038
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Indoles react smoothly with carbonyl compounds in 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4) or 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF6) ionic liquids under mild reaction conditions to afford the corresponding bis-indolylmethanes in excellent yields. These ionic liquids can be recovered and recycled in subsequent reactions without any apparent loss of activity.
引用
收藏
页码：349 / 352
页数：4
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