Adipose tissue as an endocrine organ

被引：1125
|
作者：
Ahima, RS
Flier, JS
机构：
[1] Univ Penn, Sch Med, Div Endocrinol Diabet & Metab, Philadelphia, PA 19104 USA
[2] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Div Endocrinol, Boston, MA 02215 USA
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2000年 / 11卷 / 08期
关键词：
D O I：
10.1016/S1043-2760(00)00301-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The discovery of leptin in the mid-1990s has focused attention on the role of proteins secreted by adipose tissue. Leptin has profound effects on appetite and energy balance, and is also involved in the regulation of neuroendocrine and immune function. Sex steroid and glucocorticoid metabolism in adipose tissue has been implicated as a determinant of body fat distribution and cardiovascular risk. Other adipose products, for example, proinflammatory cytokines, complement factors and components of the coagulation/fibrinolytic cascade, may mediate the metabolic and cardiovascular complications associated with obesity.
引用
收藏
页码：327 / 332
页数：6
相关论文
共 50 条
  • [11] The adipose tissue as an endocrine organ
    Szendrödi, J
    Roden, M
    ACTA MEDICA AUSTRIACA, 2004, 31 (04) : 98 - 111
  • [12] Adipose tissue as an endocrine and paracrine organ
    Mohamed-Ali, V
    Pinkney, JH
    Coppack, SW
    INTERNATIONAL JOURNAL OF OBESITY, 1998, 22 (12) : 1145 - 1158
  • [13] Adipose tissue-an endocrine organ
    Blueher, M.
    INTERNIST, 2014, 55 (06): : 687 - 697
  • [14] Adipose tissue as an endocrine organ - Preface
    Meier, CA
    Kiess, W
    BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 19 (04) : VII - VII
  • [15] Biochemistry of adipose tissue: an endocrine organ
    Coelho, Marisa
    Oliveira, Teresa
    Fernandes, Ruben
    ARCHIVES OF MEDICAL SCIENCE, 2013, 9 (02) : 191 - 200
  • [16] Adipose tissue as an endocrine and paracrine organ
    V Mohamed-Ali
    JH Pinkney
    SW Coppack
    International Journal of Obesity, 1998, 22 : 1145 - 1158
  • [17] The adipose tissue as an endocrine organ - A nephrologists' perspective
    Chudek, Jerzy
    Adamczak, Marcin
    Nieszporek, Teresa
    Wiecek, Andrzej
    OBESITY AND THE KIDNEY, 2006, 151 : 70 - 90
  • [18] Adipose tissue: an endocrine gland and organ of immunity
    Bastard, Jean-Philippe
    Feve, Bruno
    Bruckert, Eric
    SANG THROMBOSE VAISSEAUX, 2009, 21 (08): : 343 - 346
  • [19] Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ
    Trayhurn, P
    Beattie, JH
    PROCEEDINGS OF THE NUTRITION SOCIETY, 2001, 60 (03) : 329 - 339
  • [20] Perivascular Adipose Tissue as an Endocrine Organ: The Role of Statins
    Sanna, Fabio
    Margaritis, Marios
    Antoniades, Charalambos
    CURRENT PHARMACEUTICAL DESIGN, 2017, 23 (46) : 7055 - 7060
12345