The adipose tissue as an endocrine organ - A nephrologists' perspective

被引：29
作者：
Chudek, Jerzy [1 ]
Adamczak, Marcin [1 ]
Nieszporek, Teresa [1 ]
Wiecek, Andrzej [1 ]
机构：
[1] Med Univ Silesia, Dept Nephrol Endocrinol & Metab Dis, PL-40027 Katowice, Poland
来源：
OBESITY AND THE KIDNEY | 2006年 / 151卷
关键词：
D O I：
10.1159/000095320
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
During the last decade white adipose tissue was recognized as an active endocrine organ and a source of many proinflammatory cytokines, chemokines, growth factors and complement proteins called 'adipokines' or 'adipocytokines'. The contribution of different cell types which compose the adipose tissue: adipocytes, preadipocytes, stromal/vascular cells and macrophages in secretion of above-mentioned adipokines varies remarkably. These adipokines seem to play an important role in the pathogenesis of obesity-related comorbidities. In this review, we have summarized the present knowledge on the most important adipokines in patients with obesity, arterial hypertension and chronic kidney diseases. Copyright (c) 2006 S. Karger AG, Basel.
引用
收藏
页码：70 / 90
页数：21
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