SYNPHOS:: A new atropisomeric diphosphine ligand.: From laboratory-scale synthesis to scale-up development

被引：71
|
作者：
de Paule, SD
Jeulin, S
Ratovelomanana-Vidal, V
Genêt, JP
Champion, N
Deschaux, G
Dellis, P
机构：
[1] ENSCP, Lab Synthese Select Organ & Prod Nat, F-75231 Paris 05, France
[2] SYNKEM SAS, F-21301 Chenove, France
来源：
ORGANIC PROCESS RESEARCH & DEVELOPMENT | 2003年 / 7卷 / 03期
关键词：
D O I：
10.1021/op034016w
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new optically active diphosphine ligand, [(5,6),(5',6')-bis(ethlenedioxy)biphenyl-2,2'-diyl]bis(diphenylphosphine) (SYNPHOS) has been synthesized. Laboratory-scale synthesis and scale-up development of this ligand are described herein. This new atropisomeric diphosphine was also used in ruthenium-catalyzed asymmetric hydrogenation.
引用
收藏
页码：399 / 406
页数：8
相关论文
共 50 条
  • [21] Scale-up micropropagation of vegetable species: From laboratory to commercial reality
    Kintzios, S
    Konstas, J
    PROCEEDINGS OF THE FIRST INTERNATIONAL SYMPOSIUM ON ACCLIMATIZATION AND ESTABLISHMENT OF MICROPROPAGATED PLANTS, 2003, (616): : 95 - 104
  • [22] Synthesis of Laboratory Nylon: A Scale-Up Method for High Molecular Weight Polyamides
    Meyer, Peter M.
    Forrester, Michael
    Cochran, Eric W.
    INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2024, 63 (45) : 19506 - 19514
  • [23] MINOR CONSTITUENTS OF SYNTHESIS GAS FROM A LABORATORY-SCALE WOOD GASIFIER
    COUSINS, WJ
    NEW ZEALAND JOURNAL OF SCIENCE, 1983, 26 (01): : 25 - 30
  • [24] Fast Scale-Up Using Microreactors: Pyrrole Synthesis from Micro to Production Scale
    Nieuwland, Pieter J.
    Segers, Ruth
    Koch, Kaspar
    van Hest, Jan C. M.
    Rutjes, Floris P. J. T.
    ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2011, 15 (04) : 783 - 787
  • [25] Experimental investigation on self-sustained smouldering of food-processing sludge with extremely high moisture content: From laboratory-scale to pilot-scale volumetric scale-up
    Ma, Lun
    Yan, Chao
    Feng, Chao
    Qiao, Yu
    Huang, Jingchun
    Fang, Qingyan
    Zhang, Cheng
    WASTE MANAGEMENT, 2023, 158 : 13 - 22
  • [26] From micrograms to grams: scale-up synthesis of eribulin mesylate
    Yu, Melvin J.
    Zheng, Wanjun
    Seletsky, Boris M.
    NATURAL PRODUCT REPORTS, 2013, 30 (09) : 1158 - 1164
  • [27] Scale-Up and Development of a One-Step Process for the Synthesis of Succinylcholine
    Sharma, Brijesh M.
    Telang, Nakul
    Cook, Daniel W.
    Burns, Justina M.
    Stringham, Rodger W.
    Donsbach, Kai O.
    Yue, Tai-Yuen
    ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2023, 28 (01) : 248 - 257
  • [28] Development and Scale-up of the Rapid Synthesis of Triphenyl Phosphites in Continuous Flow
    Mao, Mengmei
    Zhang, Le
    Yao, Hanlin
    Wan, Li
    Xin, Zhong
    ACS OMEGA, 2020, 5 (16): : 9503 - 9509
  • [29] From laboratory to industrial scale: a scale-up framework for chemical processes in life cycle assessment studies
    Piccinno, Fabiano
    Hischier, Roland
    Seeger, Stefan
    Som, Claudia
    JOURNAL OF CLEANER PRODUCTION, 2016, 135 : 1085 - 1097
  • [30] Scale-Up Synthesis of IID572: A New β-Lactamase Inhibitor
    Furegati, Markus
    Nocito, Sandro
    Reck, Folkert
    Casarez, Anthony
    Simmons, Robert
    Schuetz, Heiner
    Koch, Guido
    ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2020, 24 (07) : 1244 - 1253
12345