Localization of cytochrome P450 3A (CYP3A) protein and detection of CYP3A4 and 3A7 mRNA by RT-PCR in human gastrointestinal tract

被引:0
|
作者
Kakiki, M
Doy, M
Yokose, T
Sawa, Y
Tadano, K
机构
[1] Eisai & Co Ltd, Tsukuba Res Labs, Drug Metab Res Sect, Ibaraki, Osaka, Japan
[2] Tsukuba Med Ctr, Dept Pathol Sect, Ibaraki, Osaka, Japan
[3] Natl Canc Ctr, Res Inst, Chiba, Japan
来源
FASEB JOURNAL | 1997年 / 11卷 / 09期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
P315
引用
收藏
页码:A825 / A825
页数:1
相关论文
共 50 条
  • [31] Isolation of cytochrome P450 3A (CYP3A) inhibitors from Hyuganatsu, Citrus tamurana Hort.
    Shinzo Hosoi
    Eri Shimizu
    Noriyuki Usami
    Ikuo Yamamoto
    Kazuhiko Arimori
    Manabu Okumura
    Muneaki Hidaka
    Mitsuko Yamada
    Akiyo Sakushima
    Journal of Natural Medicines, 2006, 60 : 240 - 242
  • [32] Investigations with a humanised CYP3A4/3A7 mouse model
    Doyle, Eddie
    Coutant, Anne-Laure
    Kapelyukh, Yury
    Boulenc, Xavier
    TOXICOLOGY LETTERS, 2014, 229 : S41 - S42
  • [33] Oxidase uncoupling in heme monooxygenases: Human cytochrome P450 CYP3A4 in Nanodiscs
    Grinkova, Yelena V.
    Denisov, Ilia G.
    McLean, Mark A.
    Sligar, Stephen G.
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 430 (04) : 1223 - 1227
  • [34] Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213
    Denisov, Ilia G.
    Grinkova, Yelena, V
    Nandigrami, Prithviraj
    Shekhar, Mrinal
    Tajkhorshid, Emad
    Sligar, Stephen G.
    BIOCHEMISTRY, 2019, 58 (10) : 1411 - 1422
  • [35] The effects of pregnancy on cytochrome P450 3A (CYP3A) and P-glycoprotein (P-gp) activity.
    Hebert, MF
    Unadkat, JD
    Carr, DB
    Kirby, B
    Eckert, L
    Easterling, TR
    JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION, 2006, 13 (02) : 227A - 227A
  • [36] A Comprehensive Investigation of Dog Cytochrome P450 3A (CYP3A) Reveals a Functional Role of Newly Identified CYP3A98 in Small Intestine
    Uno, Yasuhiro
    Jikuya, Shiori
    Noda, Yutaro
    Murayama, Norie
    Yamazaki, Hiroshi
    DRUG METABOLISM AND DISPOSITION, 2023, 51 (01) : 38 - 45
  • [37] CYP3A4 EXPRESSED BY INSECT CELLS INFECTED WITH A RECOMBINANT BACULOVIRUS CONTAINING BOTH CYP3A4 AND HUMAN NADPH-CYTOCHROME P450 REDUCTASE IS CATALYTICALLY SIMILAR TO HUMAN LIVER MICROSOMAL CYP3A4
    LEE, CA
    KADWELL, SH
    KOST, TA
    SERABJITSINGH, CJ
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1995, 319 (01) : 157 - 167
  • [38] Mechanism-based inactivation of cytochrome P450 3A (CYP3A) by HIV protease inhibitors (PI's)
    Ernest, CS
    Hall, SD
    Jones, DR
    DRUG METABOLISM REVIEWS, 2003, 35 : 170 - 170
  • [39] Tobacco and other drug dependence increases variation in cytochrome P450 3A activity (CYP3A) in females.
    Sellers, EM
    Kaplan, HL
    Somer, G
    Tyndale, RF
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 1997, 61 (02) : PI108 - PI108
  • [40] Tissue distribution of cytochrome P450 3A (CYP3A) in brushtail possums (Trichosurus vulpecula) exposed to Eucalyptus terpenes
    Sorensen, Jennifer S.
    Forbey, Kristian C.
    Tanquay, Robert L.
    McLeod, Bernie
    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 2007, 145 (02): : 194 - 201