Intramolecular nucleophilic aromatic substitution reaction of 2-carboxamido-3-arylquinazolin-4-ones and its application to the synthesis of secondary aryl amines

被引：4

作者：

Fuwa, H ^{[1
]}

Kobayashi, T ^{[1
]}

Tokitoh, T ^{[1
]}

Torii, Y ^{[1
]}

Natsugari, H ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan

来源：

SYNLETT | 2004年 / 14期

关键词：

heterocycles; nucleophilic aromatic substitutions; amines; tandem reactions; medicinal chemistry;

D O I：

10.1055/s-2004-8354805

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel intramolecular nucleophilic aromatic substitution reaction of 2-carboxamido-3-arylquinazolin-4-one derivatives induced by base treatment and its application to the expeditious synthesis of secondary aryl amines, including diaryl amines, are described.

引用

页码：2497 / 2500

页数：4

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