Intramolecular nucleophilic aromatic substitution reaction of 2-carboxamido-3-arylquinazolin-4-ones and its application to the synthesis of secondary aryl amines

被引：4
|
作者：
Fuwa, H [1 ]
Kobayashi, T [1 ]
Tokitoh, T [1 ]
Torii, Y [1 ]
Natsugari, H [1 ]
机构：
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan
来源：
SYNLETT | 2004年 / 14期
关键词：
heterocycles; nucleophilic aromatic substitutions; amines; tandem reactions; medicinal chemistry;
D O I：
10.1055/s-2004-8354805
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel intramolecular nucleophilic aromatic substitution reaction of 2-carboxamido-3-arylquinazolin-4-one derivatives induced by base treatment and its application to the expeditious synthesis of secondary aryl amines, including diaryl amines, are described.
引用
收藏
页码：2497 / 2500
页数：4
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