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Severe Pulmonary Toxicity Associated with Fludarabine and Possible Contribution of Rituximab
被引:5
|作者:
Disel, U.
Paydas, S.
[1
]
Yavuz, S.
Karakoc, E.
机构:
[1] Cukurova Univ, Fac Med, Dept Oncol, TR-01330 Adana, Turkey
关键词:
Fludarabine;
Pulmonary toxicity;
Rituximab;
CHRONIC LYMPHOCYTIC-LEUKEMIA;
INTERSTITIAL PNEUMONITIS;
FOLLICULAR LYMPHOMA;
PHASE-II;
THERAPY;
CLL;
D O I:
10.1159/000305255
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Fludarabine is a nucleoside analogue used in the treatment of low-grade lymphoproliferative disorders and in conditioning regimens of non-myeloablative allogeneic stem cell transplantation. This is a relatively safe drug for clinical use but may cause side effects, some of which may be life-threatening. Here a case of severe pulmonary toxicity associated with fludarabine and a possible contribution of rituximab is presented and the literature reviewed. Copyright (C) 2010 S. Karger AG, Basel
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页码:89 / 93
页数:5
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