Severe Pulmonary Toxicity Associated with Fludarabine and Possible Contribution of Rituximab

被引:5
|
作者
Disel, U.
Paydas, S. [1 ]
Yavuz, S.
Karakoc, E.
机构
[1] Cukurova Univ, Fac Med, Dept Oncol, TR-01330 Adana, Turkey
关键词
Fludarabine; Pulmonary toxicity; Rituximab; CHRONIC LYMPHOCYTIC-LEUKEMIA; INTERSTITIAL PNEUMONITIS; FOLLICULAR LYMPHOMA; PHASE-II; THERAPY; CLL;
D O I
10.1159/000305255
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Fludarabine is a nucleoside analogue used in the treatment of low-grade lymphoproliferative disorders and in conditioning regimens of non-myeloablative allogeneic stem cell transplantation. This is a relatively safe drug for clinical use but may cause side effects, some of which may be life-threatening. Here a case of severe pulmonary toxicity associated with fludarabine and a possible contribution of rituximab is presented and the literature reviewed. Copyright (C) 2010 S. Karger AG, Basel
引用
收藏
页码:89 / 93
页数:5
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