Fludarabine is a nucleoside analogue used in the treatment of low-grade lymphoproliferative disorders and in conditioning regimens of non-myeloablative allogeneic stem cell transplantation. This is a relatively safe drug for clinical use but may cause side effects, some of which may be life-threatening. Here a case of severe pulmonary toxicity associated with fludarabine and a possible contribution of rituximab is presented and the literature reviewed. Copyright (C) 2010 S. Karger AG, Basel
机构:
Long Isl Jewish Med Ctr, Div Pulm & Crit Care Med, New Hyde Pk, NY 11042 USALong Isl Jewish Med Ctr, Div Pulm & Crit Care Med, New Hyde Pk, NY 11042 USA
Stoica, GS
Greenberg, HE
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机构:
Long Isl Jewish Med Ctr, Div Pulm & Crit Care Med, New Hyde Pk, NY 11042 USALong Isl Jewish Med Ctr, Div Pulm & Crit Care Med, New Hyde Pk, NY 11042 USA
Greenberg, HE
Rossoff, LJ
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Long Isl Jewish Med Ctr, Div Pulm & Crit Care Med, New Hyde Pk, NY 11042 USALong Isl Jewish Med Ctr, Div Pulm & Crit Care Med, New Hyde Pk, NY 11042 USA
Rossoff, LJ
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS,
2002,
25
(04):
: 340
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