Non-invasive determination of the O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation status in glioblastoma (GBM) using magnetic resonance imaging (MRI)

被引:6
|
作者
Rathore, Saima
Bakas, Spyridon
Nasrallah, MacLean P.
Bagley, Stephen Joseph
Akbari, Hamed
Ha, Sung Min
Mamourian, Elizabeth Claire
Watt, Christopher D.
Davatzikos, Christos
机构
[1] Univ Pennsylvania, Perelman Sch Med, Dept Radiol, Ctr Biomed Image Comp & Analyt, Philadelphia, PA USA
[2] Univ Pennsylvania, Perelman Sch Med, Dept Pathol & Lab Med, Philadelphia, PA USA
[3] Univ Pennsylvania, Perelman Sch Med, Div Hematol Oncol, Philadelphia, PA USA
关键词
D O I
10.1200/JCO.2018.36.15_suppl.2051
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2051
引用
收藏
页数:2
相关论文
共 50 条
  • [41] The Impact of O6-Methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation on the Outcomes of Patients with Leiomyosarcoma Treated with Dacarbazine
    Cannella, Lucia
    Della Monica, Rosa
    Marretta, Antonella Lucia
    Iervolino, Domenico
    Vincenzi, Bruno
    De Chiara, Anna Rosaria
    Clemente, Ottavia
    Buonaiuto, Michela
    Barretta, Maria Luisa
    Di Mauro, Annabella
    Di Marzo, Massimiliano
    Guida, Michele
    Badalamenti, Giuseppe
    Chiariotti, Lorenzo
    Tafuto, Salvatore
    CELLS, 2023, 12 (12)
  • [42] O6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: Enzyme activity, promoter methylation and immunohistochemistry
    Christmann, Markus
    Verbeek, Barbara
    Roos, Wynand P.
    Kaina, Bernd
    BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2011, 1816 (02): : 179 - 190
  • [43] O6-METHYLGUANINE DNA METHYLTRANSFERASE (MGMT) PROMOTER METHYLATION STATUS AND THE INCIDENCE OF TEMOZOLOMIDE-INDUCED HEMATOLOGIC TOXICITY: AN ASSOCIATION STUDY
    Strohbusch, Alyssa
    Pound, Heather
    Regis, Patrick
    Cavaliere, Robert
    NEURO-ONCOLOGY, 2020, 22 : 135 - 135
  • [44] Aberrant MGMT (O6-methylguanine-DNA methyltransferase) promoter methylation is a frequent event in choroid plexus tumors
    Hasselblatt, Martin
    Muehlisch, Joerg
    Wrede, Brigitte
    Kallinger, Birgit
    Jeibmann, Astrid
    Peters, Ove
    Wolff, Johannes
    Paulus, Werner
    Fruehwald, Michael
    NEURO-ONCOLOGY, 2008, 10 (03) : 395 - 395
  • [45] Changes of O6-Methylguanine DNA Methyltransferase (MGMT) Promoter Methylation in Glioblastoma Relapse-A Meta-Analysis Type Literature Review
    Feldheim, Jonas
    Kessler, Almuth F.
    Monoranu, Camelia M.
    Ernestus, Ralf-Ingo
    Loehr, Mario
    Hagemann, Carsten
    CANCERS, 2019, 11 (12)
  • [46] The promoter methylation status of the DNA repair gene O6-methylguanine-DNA methyltransferase in ulcerative colitis
    Matsumura, S
    Oue, N
    Ito, R
    Nakayama, H
    Kitadai, Y
    Yokozaki, H
    Chayama, K
    Yasui, W
    VIRCHOWS ARCHIV, 2003, 443 (04) : 518 - 523
  • [47] The promoter methylation status of the DNA repair gene O6-methylguanine-DNA methyltransferase in ulcerative colitis
    Shunji Matsumura
    Naohide Oue
    Reiko Ito
    Hirofumi Nakayama
    Yasuhiko Kitadai
    Hiroshi Yokozaki
    Kazuaki Chayama
    Wataru Yasui
    Virchows Archiv, 2003, 443 : 518 - 523
  • [48] Determination of O6-Methylguanine DNA Methyltransferase Promoter Methylation in Non-Small Cell Lung Cancer
    Ekim, Mehmet
    Caner, Vildan
    Buyukpinarbasili, Nur
    Tepeli, Emre
    Elmas, Levent
    Bagci, Gulseren
    GENETIC TESTING AND MOLECULAR BIOMARKERS, 2011, 15 (05) : 357 - 360
  • [49] Determination of O6-methylguanine DNA methyltransferase promoter methylation in non-small cell lung cancer
    Ekim, Mehmet
    Caner, Vildan
    Buyukpinarbasili, Nur
    Tepeli, Emre
    Elmas, Levent
    Bagei, Gulseren
    CHROMOSOME RESEARCH, 2011, 19 : S186 - S186
  • [50] The Clinical Significance of O6-Methylguanine-DNA Methyltransferase Promoter Methylation Status in Adult Patients With Glioblastoma: A Meta-analysis
    Zhao, Yu-Hang
    Wang, Ze-Fen
    Cao, Chang-Jun
    Weng, Hong
    Xu, Cheng-Shi
    Li, Kai
    Li, Jie-Li
    Lan, Jing
    Zeng, Xian-Tao
    Li, Zhi-Qiang
    FRONTIERS IN NEUROLOGY, 2018, 9