Non-invasive determination of the O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation status in glioblastoma (GBM) using magnetic resonance imaging (MRI)

被引:6
|
作者
Rathore, Saima
Bakas, Spyridon
Nasrallah, MacLean P.
Bagley, Stephen Joseph
Akbari, Hamed
Ha, Sung Min
Mamourian, Elizabeth Claire
Watt, Christopher D.
Davatzikos, Christos
机构
[1] Univ Pennsylvania, Perelman Sch Med, Dept Radiol, Ctr Biomed Image Comp & Analyt, Philadelphia, PA USA
[2] Univ Pennsylvania, Perelman Sch Med, Dept Pathol & Lab Med, Philadelphia, PA USA
[3] Univ Pennsylvania, Perelman Sch Med, Div Hematol Oncol, Philadelphia, PA USA
关键词
D O I
10.1200/JCO.2018.36.15_suppl.2051
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2051
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Evaluation status and prognostic significance of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in pediatric high grade gliomas
    Francesca R. Buttarelli
    Maura Massimino
    Manila Antonelli
    Libero Lauriola
    Paolo Nozza
    Vittoria Donofrio
    Antonella Arcella
    Maria A. Oliva
    Concezio Di Rocco
    Felice Giangaspero
    Child's Nervous System, 2010, 26 : 1051 - 1056
  • [32] O6-Methylguanine-DNA Methyltransferase (MGMT) promoter methylation status of high-grade and low-grade gliomas
    Ichwan, Syaiful
    Ningsih, Hesty Lidya
    Aman, Renindra Ananda
    Tandian, David
    Ashari, Samsul
    Gunawan, Kevin
    Nugroho, Setyo Widi
    BALI MEDICAL JOURNAL, 2021, 10 (02) : 644 - 647
  • [33] O-6-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma
    Bobola, Michael S.
    Alnoor, Mohammad
    Chen, John Y. -S.
    Kolstoe, Douglas D.
    Silbergeld, Daniel L.
    Rostomily, Robert C.
    Blank, A.
    Chamberlain, Marc C.
    Silber, John R.
    BBA CLINICAL, 2015, 3 : 1 - 10
  • [34] Analysis of the status of O6-methylguanine-DNA methyltransferase (MGMT) gene promoter methylation in different topographical samples, as well as during progression ad recurrence of glioblastoma
    Barresi, V.
    Caffo, M.
    Simone, A.
    Scarfi, R.
    Tuccari, G.
    Giuffre, G.
    VIRCHOWS ARCHIV, 2016, 469 : S12 - S12
  • [35] Relationship between glioblastoma location and O6-methylguanine-DNA methyltransferase promoter methylation percentage
    Sansone, Giulio
    Lombardi, Giuseppe
    Maccari, Marta
    Gaiola, Matteo
    Pini, Lorenzo
    Cerretti, Giulia
    Guerriero, Angela
    Volpin, Francesco
    Denaro, Luca
    Corbetta, Maurizio
    Salvalaggio, Alessandro
    BRAIN COMMUNICATIONS, 2024, 6 (06)
  • [36] O6-methylguanine-DNA methyltransferase activity and promoter methylation status in pediatric rhabdomyosarcoma
    Yeager, ND
    Dolan, ME
    Gastier, JM
    Gross, TG
    Delaney, S
    Frick, J
    Ruymann, FB
    Ewesuedo, R
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2003, 25 (12) : 941 - 947
  • [37] O6-methylguanine DNA methyltransferase gene promoter methylation status in glioblastoma and its correlation with other prognostic markers
    Lee, Sung Hak
    Nam, Suk Woo
    Hong, Yong Gil
    Kang, Chang Suk
    Lee, Youn Soo
    MOLECULAR & CELLULAR TOXICOLOGY, 2011, 7 (04) : 425 - 430
  • [38] O6-methylguanine DNA methyltransferase gene promoter methylation status in glioblastoma and its correlation with other prognostic markers
    Sung Hak Lee
    Suk Woo Nam
    Yong Gil Hong
    Chang Suk Kang
    Youn Soo Lee
    Molecular & Cellular Toxicology, 2011, 7 : 425 - 430
  • [39] O6-Methylguanine-DNA Methyltransferase (MGMT) mRNA Expression Predicts Outcome in Malignant Glioma Independent of MGMT Promoter Methylation
    Kreth, Simone
    Thon, Niklas
    Eigenbrod, Sabina
    Lutz, Juergen
    Ledderose, Carola
    Egensperger, Rupert
    Tonn, Joerg C.
    Kretzschmar, Hans A.
    Hinske, Ludwig C.
    Kreth, Friedrich W.
    PLOS ONE, 2011, 6 (02):
  • [40] TREATMENT PATTERNS BY O6-METHYLGUANINE DNA METHYLTRANSFERASE PROMOTER (MGMT) STATUS IN NEWLY-DIAGNOSED GLIOBLASTOMA MULTIFORME (GBM): A MULTI-COUNTRY CHART REVIEW STUDY
    Fu, A. Z.
    Thompson, G. J.
    Hall, J. P.
    Bailey, A.
    Kemp, J.
    Lee, C.
    NEURO-ONCOLOGY, 2019, 21 : 75 - 75