Epidemiological studies of the non-specific effects of vaccines: II - methodological issues in the design and analysis of cohort studies

被引：37
|
作者：
Farrington, C. P. [1 ]
Firth, M. J. [2 ,3 ]
Moulton, L. H. [4 ]
Ravn, H. [5 ]
Andersen, P. K. [6 ]
Evans, S. [7 ]
机构：
[1] Open Univ, Dept Math & Stat, Milton Keynes MK7 6AA, Bucks, England
[2] Univ Western Australia, Telethon Inst Child Hlth Res, Nedlands, WA 6009, Australia
[3] Univ Western Australia, Ctr Child Hlth Res, Nedlands, WA 6009, Australia
[4] Johns Hopkins Univ, Div Int Hlth, Baltimore, MD USA
[5] Statens Serum Inst, Bandim Hlth Project, DK-2300 Copenhagen, Denmark
[6] Univ Copenhagen, Dept Biostat, Copenhagen, Denmark
[7] London Sch Hyg & Trop Med, London WC1, England
来源：
TROPICAL MEDICINE & INTERNATIONAL HEALTH | 2009年 / 14卷 / 09期
基金：
英国惠康基金; 英国医学研究理事会;
关键词：
vaccines; mortality; non-specific effects; methodology; CHILD SURVIVAL; ROUTINE IMMUNIZATIONS; PROPENSITY SCORE; GUINEA-BISSAU; VACCINATION; MORTALITY; SITUATION;
D O I：
10.1111/j.1365-3156.2009.02302.x
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
We review sources of bias which can affect non-randomized cohort studies of non-specific effects of vaccines on child mortality. Using examples from the literature on non-specific effects, we describe different sources of selection and information bias, and, where possible, outline analysis strategies to mitigate or eliminate such biases.
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页码：977 / 985
页数：9
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