Epidemiological studies of the non-specific effects of vaccines: II - methodological issues in the design and analysis of cohort studies

被引：37

作者：

Farrington, C. P. ^{[1
]}

Firth, M. J. ^{[2
,3
]}

Moulton, L. H. ^{[4
]}

Ravn, H. ^{[5
]}

Andersen, P. K. ^{[6
]}

Evans, S. ^{[7
]}

机构：

[1] Open Univ, Dept Math & Stat, Milton Keynes MK7 6AA, Bucks, England

[2] Univ Western Australia, Telethon Inst Child Hlth Res, Nedlands, WA 6009, Australia

[3] Univ Western Australia, Ctr Child Hlth Res, Nedlands, WA 6009, Australia

[4] Johns Hopkins Univ, Div Int Hlth, Baltimore, MD USA

[5] Statens Serum Inst, Bandim Hlth Project, DK-2300 Copenhagen, Denmark

[6] Univ Copenhagen, Dept Biostat, Copenhagen, Denmark

[7] London Sch Hyg & Trop Med, London WC1, England

来源：

TROPICAL MEDICINE & INTERNATIONAL HEALTH | 2009年 / 14卷 / 09期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

vaccines; mortality; non-specific effects; methodology; CHILD SURVIVAL; ROUTINE IMMUNIZATIONS; PROPENSITY SCORE; GUINEA-BISSAU; VACCINATION; MORTALITY; SITUATION;

D O I：

10.1111/j.1365-3156.2009.02302.x

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We review sources of bias which can affect non-randomized cohort studies of non-specific effects of vaccines on child mortality. Using examples from the literature on non-specific effects, we describe different sources of selection and information bias, and, where possible, outline analysis strategies to mitigate or eliminate such biases.

引用

页码：977 / 985

页数：9

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