Iridium-Catalyzed Asymmetric Hydrogenation of Cyclic Enamines

被引：137
|
作者：
Hou, Guo-Hua
Xie, Jian-Hua
Yan, Pu-Cha
Zhou, Qi-Lin [1 ]
机构：
[1] Nankai Univ, State Key Lab, Tianjin 300071, Peoples R China
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 04期
基金：
中国国家自然科学基金;
关键词：
AMINO-ACID-DERIVATIVES; ENANTIOSELECTIVE HYDROGENATION; ALLYLIC AMINATION; LIGANDS; PHOSPHORAMIDITE; ETHERIFICATION; COMPLEXES; ALKALOIDS; ARYL;
D O I：
10.1021/ja808358r
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first highly enantioselective iridium-catatyzed hydrogenation of cyclic enamines has been developed. This new reaction provided an efficient method for the synthesis of optically active cyclic tertiary amines including natural product crispine A.
引用
收藏
页码：1366 / +
页数：3
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