Iridium-Catalyzed Asymmetric Hydrogenation of Cyclic Enamines

被引：137
|
作者：
Hou, Guo-Hua
Xie, Jian-Hua
Yan, Pu-Cha
Zhou, Qi-Lin [1 ]
机构：
[1] Nankai Univ, State Key Lab, Tianjin 300071, Peoples R China
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 131卷 / 04期
基金：
中国国家自然科学基金;
关键词：
AMINO-ACID-DERIVATIVES; ENANTIOSELECTIVE HYDROGENATION; ALLYLIC AMINATION; LIGANDS; PHOSPHORAMIDITE; ETHERIFICATION; COMPLEXES; ALKALOIDS; ARYL;
D O I：
10.1021/ja808358r
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first highly enantioselective iridium-catatyzed hydrogenation of cyclic enamines has been developed. This new reaction provided an efficient method for the synthesis of optically active cyclic tertiary amines including natural product crispine A.
引用
收藏
页码：1366 / +
页数：3
相关论文
共 50 条
  • [21] Iridium-catalyzed asymmetric hydrogenation of N-phosphinoylimine
    Yin, Congcong
    Pan, Yingmin
    Zheng, Longsheng
    Lin, Bijin
    Wen, Jialin
    Zhang, Xumu
    ORGANIC CHEMISTRY FRONTIERS, 2021, 8 (06) : 1223 - 1226
  • [22] Iridium-catalyzed asymmetric hydrogenation of unfunctionalized tetrasubstituted Olefins
    Schrems, Marcus G.
    Neumann, Eva
    Pfaltz, Andreas
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (43) : 8274 - 8276
  • [23] Iridium-Catalyzed Asymmetric Hydrogenation of Sterically Hindered Cyclic Imines for Enantioselective Synthesis of Tetrahydroisoquinolines
    Li, Bin
    Liu, Ruixia
    Yang, Jing
    Luo, Jingyuan
    Yao, Lin
    Li, Muqiong
    Zheng, Xiaohui
    Jiang, Ru
    Nie, Huifang
    Zhang, Shengyong
    ORGANIC LETTERS, 2021, 23 (01) : 140 - 144
  • [24] Iridium-Catalyzed Asymmetric Hydrogenation of Unsaturated Carboxylic Acids
    Zhu, Shou-Fei
    Zhou, Qi-Lin
    ACCOUNTS OF CHEMICAL RESEARCH, 2017, 50 (04) : 988 - 1001
  • [25] Highly Enantioselective Iridium-Catalyzed Hydrogenation of Cyclic Enamides
    Salomo, Ernest
    Orgue, Silvia
    Riera, Antoni
    Verdaguer, Xavier
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 55 (28) : 7988 - 7992
  • [26] Iridium-catalyzed asymmetric transfer hydrogenation of quinolines with Hantzsch esters
    Wang, Da-Wei
    Zeng, Wei
    Zhou, Yong-Gui
    TETRAHEDRON-ASYMMETRY, 2007, 18 (09) : 1103 - 1107
  • [27] Highly efficient iridium-catalyzed asymmetric hydrogenation of β-acylamino nitroolefins
    Yan, Qiaozhi
    Liu, Man
    Kong, Duanyang
    Zi, Guofu
    Hou, Guohua
    CHEMICAL COMMUNICATIONS, 2014, 50 (85) : 12870 - 12872
  • [28] Rationally designed ligands for asymmetric iridium-catalyzed hydrogenation of olefins
    Källström, K
    Hedberg, C
    Brandt, P
    Bayer, A
    Andersson, PG
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (44) : 14308 - 14309
  • [29] Methylaluminoxane as an Alternative for BArF in the Iridium-Catalyzed Asymmetric Hydrogenation of Imines
    Mrsic, Natasa
    Panella, Lavinia
    IJpeij, Edwin G.
    Minnaard, Adriaan J.
    Feringa, Ben L.
    de Vries, Johannes G.
    CHEMCATCHEM, 2011, 3 (07) : 1139 - 1142
  • [30] Iridium-Catalyzed Asymmetric Hydrogenation of N-Protected Indoles
    Baeza, Alejandro
    Pfaltz, Andreas
    CHEMISTRY-A EUROPEAN JOURNAL, 2010, 16 (07) : 2036 - 2039
12345