Synthesis and Crystal Structure of 3-{[(1E) 1-(2-Hydroxyphenyl) methylidene]amino}-4-cyanopyrazole

被引：0

作者：

Cheng Qing-Fang ^{[1
,2
]}

Xu Xing-You ^{[1
,2
]}

Wang Qi-Fa ^{[3
]}

Qian Bao-Hua ^{[2
]}

Liu Wang-Jun ^{[2
]}

Yang Xu-Jie ^{[1
]}

机构：

[1] Nanjing Univ Sci & Technol, Mat Chem Lab, Nanjing 210094, Peoples R China

[2] Huaihai Inst Technol, Dept Chem Technol, Lianyungang 222005, Peoples R China

[3] Huaihai Inst Technol, Jiangsu Key Lab Marine Biotechnol, Lianyungang 222005, Peoples R China

来源：

CHINESE JOURNAL OF STRUCTURAL CHEMISTRY | 2009年 / 28卷 / 10期

关键词：

Schiff base; pyrazole derivative; crystal structure; antibacterial activities; SCHIFF-BASE; S-BENZYLDITHIOCARBAZATE; COMPLEXES;

D O I：

暂无

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The title Schiff base compound (C11H8N4O), a derivative of pyrazole, has been synthesized by the reaction of salicylaldehyde and 3-amino-4-cyanopyrazole in absolute ethanol and characterized by elemental analyses, IR, H-1 NMR and X-ray single-crystal diffraction. The crystal belongs to the monoclinic system, space group P2(1)/n, with a = 7.5594(7), b = 18.3342(19), c = 22.461(2) angstrom, beta = 98.419(2)degrees, V = 3079.5(5) angstrom(3), M-r = 212.21, Z 12, F(000) = 1320, D-c = 1.373 g/cm(3), T = 298(2) K, lambda = 0.71073 angstrom, the final R = 0.0571 and wR 0.0493. A total of 5412 unique reflections were collected, of which 1612 with I > 2 sigma(I) were observed. The molecular structure adopts a trans configuration about the C=N double bond. The preliminary biological tests show that the compound has high antibacterial activities.

引用

页码：1281 / 1285

页数：5

共 50 条

[31] Synthesis and Crystal Structure of 4-{[(1E)1-(2-Hydroxy-3-methoxyphenyl)methylidene]amino}-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
孙玉希
结构化学, 2007, (01) : 55 - 58
[32] Crystal Structure and Hirshfeld Surfaces of (E)-1-(2-Hydroxyphenyl)-3-(5-methylthiophen-2-yl)prop-2-en-1-one
Sreenatha, N. R.
Lakshminarayana, B. N.
Ganesha, D. P.
Vijayshankar, S.
Nagaraju, S.
X-RAY STRUCTURE ANALYSIS ONLINE, 2018, 34 : 23 - 24
[33] Synthesis and crystal structure of 4-{[(1E)1-(2-hydroxy-3-methoxyphenyl)methylidene]amino}-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
Sun Yu-Xi
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2007, 26 (01) : 55 - 58
[34] Crystal structure of (E)-1-(4-(benzyloxy)-2-hydroxyphenyl)-3-(dimethylamino)prop-2-en-1-one, C18H19NO3
Wang, Hua-Bin
Xu, Lian-Hua
Shi, Ju-Mei
Li, Wei-Zhong
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2024, 239 (02): : 239 - 240
[35] (2E)-1-(2-hydroxyphenyl)-3-[4-(methylsulfanyl)phenyl]prop-2-en-1-one
Sarojini, B. K.
Yathirajan, H. S.
Mustafa, K.
Sarfraz, H.
Bolte, Michael
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O4448 - U4652
[36] Crystal structure of 3-(prop-2-en-1-yl)-1-{[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidene]amino]thiourea
Mague, Joel T.
Mohamed, Shaaban K.
Akkurt, Mehmet
Hassan, Alaa A.
Abdel-Aziz, Ahmed T.
Albayati, Mustafa R.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2015, 71 : O976 - U853
[37] (E)-3-(3,4-Dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one
Jasinski, Jerry P.
Butcher, Ray J.
Khaleel, V. Musthafa
Sarojini, B. K.
Yathirajan, H. S.
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O845 - U232
[38] Synthesis and Crystal Structure of (E)-2-(1-(2-Hydroxy-4-methoxyphenyl)ethylideneamino)-3-(4-hydroxyphenyl)methyl Propionate
李旭
陈晓岚
袁金伟
朱海生
屈凌波
结构化学, 2013, 32 (05) : 751 - 755
[39] Synthesis and Crystal Structure of (E)-2-(1-(2-Hydroxy-4-methoxyphenyl)ethylideneamino)-3-(4-hydroxyphenyl)methyl Propionate
Li Xu
Chen Xiao-Lan
Yuan Jin-Wei
Zhu Hai-Sheng
Qu Ling-Bo
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2013, 32 (05) : 751 - 755
[40] 2-{(Z)-2-[(E)-1-(2-Hydroxyphenyl)methylidene]hydrazono}-1,2-diphenylethan-1-one
Abbasi, Alireza
Ziarani, Ghodsi Mohammadi
Tarighi, Sara
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O2579 - O2580

← 1 2 3 4 5 →