Synthesis and Crystal Structure of 3-{[(1E) 1-(2-Hydroxyphenyl) methylidene]amino}-4-cyanopyrazole

被引：0
|
作者：
Cheng Qing-Fang [1 ,2 ]
Xu Xing-You [1 ,2 ]
Wang Qi-Fa [3 ]
Qian Bao-Hua [2 ]
Liu Wang-Jun [2 ]
Yang Xu-Jie [1 ]
机构：
[1] Nanjing Univ Sci & Technol, Mat Chem Lab, Nanjing 210094, Peoples R China
[2] Huaihai Inst Technol, Dept Chem Technol, Lianyungang 222005, Peoples R China
[3] Huaihai Inst Technol, Jiangsu Key Lab Marine Biotechnol, Lianyungang 222005, Peoples R China
来源：
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY | 2009年 / 28卷 / 10期
关键词：
Schiff base; pyrazole derivative; crystal structure; antibacterial activities; SCHIFF-BASE; S-BENZYLDITHIOCARBAZATE; COMPLEXES;
D O I：
暂无
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The title Schiff base compound (C11H8N4O), a derivative of pyrazole, has been synthesized by the reaction of salicylaldehyde and 3-amino-4-cyanopyrazole in absolute ethanol and characterized by elemental analyses, IR, H-1 NMR and X-ray single-crystal diffraction. The crystal belongs to the monoclinic system, space group P2(1)/n, with a = 7.5594(7), b = 18.3342(19), c = 22.461(2) angstrom, beta = 98.419(2)degrees, V = 3079.5(5) angstrom(3), M-r = 212.21, Z 12, F(000) = 1320, D-c = 1.373 g/cm(3), T = 298(2) K, lambda = 0.71073 angstrom, the final R = 0.0571 and wR 0.0493. A total of 5412 unique reflections were collected, of which 1612 with I > 2 sigma(I) were observed. The molecular structure adopts a trans configuration about the C=N double bond. The preliminary biological tests show that the compound has high antibacterial activities.
引用
收藏
页码：1281 / 1285
页数：5
相关论文
共 50 条
  • [21] (2E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one
    Sarojini, B. K.
    Yathirajan, H. S.
    Mustafa, K.
    Sarfraz, H.
    Bolte, Michael
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O4477 - U4919
  • [22] Synthesis and Crystal Structure of 1-(2,6-Dichloro-4-nitrophenyl)-5-amino-4-cyanopyrazole
    林秋莲
    钟平
    骆毅
    结构化学, 2008, (07) : 836 - 840
  • [23] (E)-1-(2-Hydroxyphenyl)-3-(2,4,5-trimethoxyphenyl)prop-2-en-1-one
    Fun, Hoong-Kun
    Suwunwong, Thitipone
    Chanawanno, Kullapa
    Wisitsak, Pitikan
    Chantrapromma, Suchada
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2287 - U2221
  • [24] (2E)-3-[3-(Benzyloxy)phenyl]-1-(2-hydroxyphenyl)prop-2-en-1-one
    Fun, Hoong-Kun
    Loh, Wan-Sin
    Sarojini, B. K.
    Khaleel, V. Musthafa
    Narayana, B.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O1313 - U1922
  • [25] N-(2-{[(1E)-1-(2-hydroxyphenyl)ethyl-idene]amino}phenyl)-2-methoxyacetamide
    Yildirim, Sema Oeztuerk
    Akkurt, Mehmet
    Jarrahpour, Ali Asghar
    Rezaei, Shadab
    Heinemann, Frank W.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O3478 - U3186
  • [26] 3-(4-Chlorophenyl)-1-(2-hydroxyphenyl)-prop-2-en-1-one
    Fun, Hoong-Kun
    Patil, P. S.
    Dharmaprakash, S. M.
    Chantrapromma, Suchada
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O561 - O562
  • [27] (E)-3-(2-Furyl)-1-(2-hydroxyphenyl)prop-2-en-1-one
    Kong, Lingqian
    Liu, Yanhong
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O2161 - U2347
  • [28] Synthesis and crystal structure of 1-(2,6-dichloro-4-nitrophenyl)-5-amino-4-cyanopyrazole
    Lin Qiu-Lian
    Zhong Ping
    Luo Yi
    CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2008, 27 (07) : 836 - 840
  • [29] Synthesis and Crystal Structure of 1-(2,6-Dichloro-4-nitrophenyl)-5-amino-4-cyanopyrazole
    林秋莲
    钟平
    骆毅
    Chinese Journal of Structural Chemistry, 2008, (07) : 836 - 840
  • [30] Synthesis and Crystal Structure of 4-{[(1E)1-(2-Hydroxy-3-methoxyphenyl)methylidene]amino}-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
    孙玉希
    Chinese Journal of Structural Chemistry, 2007, (01) : 55 - 58
12345