A host-guest system based on collagen-like triple-helix hybridization

被引：6
|
作者：
Delsuc, N. [1 ]
Uchinomiya, S. [2 ]
Ojida, A. [2 ]
Hamachi, I. [3 ]
机构：
[1] UPMC Univ Paris 06, Sorbonne Univ, PSL Res Univ, Lab Biomol,Dept Chim,Ecole Normale Super,CNRS, 24 Rue Lhomond, F-75005 Paris, France
[2] Kyushu Univ, Grad Sch Pharmaceut Sci, Higashi Ku, 3-1-1 Maidashi, Fukuoka, Fukuoka, Japan
[3] Kyoto Univ, Grad Sch Engn, Dept Synthet Chem & Biol Chem, Kyoto, Japan
来源：
CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 51期
基金：
日本学术振兴会;
关键词：
DIKETOPIPERAZINE RECEPTORS; MOLECULAR RECOGNITION; MODEL; PEPTIDES; BINDING; PROBE; WATER; STABILIZATION; TRANSITION; STABILITY;
D O I：
10.1039/c7cc03055j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A strategy inspired by tweezer receptors has been employed to develop a new host-guest system. The hybridization into a collagen-like triple helix is the driving force for the recognition that occurs with high affinity and selectivity. Several systems have been screened to find the best host-guest pair and this strategy may be implemented for tag fused protein recognition.
引用
收藏
页码：6856 / 6859
页数：4
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