How to manage IBD in the 'elderly'

被引:7
|
作者
Segal, Jonathan P. [1 ]
Htet, Hein Myat Thu [2 ]
Limdi, Jimmy [3 ,4 ]
Hayee, Bu'Hussain [5 ]
机构
[1] St Marks Hosp, Dept Gastroenterol, Watford, England
[2] Barts Hlth NHS Trust, Gastroenterol, London, England
[3] Pennine Acute Hosp NHS Trust, Div Gastroenterol, Sect IBD, Manchester, Lancs, England
[4] Manchester Acad Hlth Sci Ctr, Dept Gastroenterol, Manchester, Lancs, England
[5] Kings Coll Hosp London, Dept Gastroenterol, London, England
关键词
INFLAMMATORY-BOWEL-DISEASE; REFRACTORY CROHNS-DISEASE; EVIDENCE-BASED CONSENSUS; ANTI-TNF THERAPY; ULCERATIVE-COLITIS; MAINTENANCE THERAPY; CLINICAL PHARMACOKINETICS; OPPORTUNISTIC INFECTIONS; COLORECTAL-CANCER; RISK-FACTORS;
D O I
10.1136/flgastro-2019-101218
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
As the incidence of inflammatory bowel disease (IBD) rises and the global population ages, the number of older people living with these conditions will inevitably increase. The challenges posed by comorbid conditions, polypharmacy, the unintended consequences of long-term treatment and the real but often underestimated mismatch between chronological and biological ages underpin management. Significantly, there may be differences in disease characteristics, presentation and management of an older patient with IBD, together with other unique challenges. Importantly, clinical trials often exclude older patients, so treatment decisions are frequently pragmatic, extrapolated from a number of sources of evidence and perhaps primarily dictated by concerns around adverse effects. This review aimed to discuss the epidemiology, clinical features and considerations with management in older patients with IBD.
引用
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页码:468 / 477
页数:10
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