As the incidence of inflammatory bowel disease (IBD) rises and the global population ages, the number of older people living with these conditions will inevitably increase. The challenges posed by comorbid conditions, polypharmacy, the unintended consequences of long-term treatment and the real but often underestimated mismatch between chronological and biological ages underpin management. Significantly, there may be differences in disease characteristics, presentation and management of an older patient with IBD, together with other unique challenges. Importantly, clinical trials often exclude older patients, so treatment decisions are frequently pragmatic, extrapolated from a number of sources of evidence and perhaps primarily dictated by concerns around adverse effects. This review aimed to discuss the epidemiology, clinical features and considerations with management in older patients with IBD.
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Sch Med Federico II Naples, Dept Clin Med & Surg, Gastroenterol, Naples, ItalySch Med Federico II Naples, Dept Clin Med & Surg, Gastroenterol, Naples, Italy
Castiglione, Fabiana
Imperatore, Nicola
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Sch Med Federico II Naples, Dept Clin Med & Surg, Gastroenterol, Naples, ItalySch Med Federico II Naples, Dept Clin Med & Surg, Gastroenterol, Naples, Italy
Imperatore, Nicola
Zingone, Fabiana
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Univ Padua, Azienda Osped, Dept Surg Oncol & Gastroenterol, Padua, ItalySch Med Federico II Naples, Dept Clin Med & Surg, Gastroenterol, Naples, Italy
Zingone, Fabiana
D'Inca, Renata
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Univ Padua, Azienda Osped, Dept Surg Oncol & Gastroenterol, Padua, Italy
Azienda Univ, Via Giustiniani 2, Padua, ItalySch Med Federico II Naples, Dept Clin Med & Surg, Gastroenterol, Naples, Italy
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Georgia State Univ, J Mack Robinson Coll Business, Mkt, Atlanta, GA 30303 USA
Georgia State Univ, Ctr Mature Consumer Studies, Atlanta, GA 30303 USAGeorgia State Univ, J Mack Robinson Coll Business, Mkt, Atlanta, GA 30303 USA
Moschis, George P.
Burkhalter, Janee N.
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Georgia State Univ, J Mack Robinson Coll Business, Atlanta, GA 30303 USAGeorgia State Univ, J Mack Robinson Coll Business, Mkt, Atlanta, GA 30303 USA