Determination of Theophylline at a Cysteic Acid Modified Glassy Carbon Electrode

被引:40
|
作者
Brunetti, Barbara [1 ]
Desimoni, Elio [1 ]
机构
[1] Univ Milan, DISTAM, I-20133 Milan, Italy
关键词
Modified electrodes; Cysteine; Cysteic acid; Theophylline; Voltammetry; PARTIAL LEAST-SQUARES; PERFORMANCE LIQUID-CHROMATOGRAPHY; CONDUCTIVE DIAMOND ELECTRODES; CHEMICALLY-MODIFIED ELECTRODE; VOLTAMMETRIC DETERMINATION; ELECTROCHEMICAL OXIDATION; AMPEROMETRIC DETECTION; CAFFEINE; THEOBROMINE; HPLC;
D O I
10.1002/elan.200804477
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A glassy carbon electrode modified with electrodeposited cysteic acid is proposed for the determination of theophylline. Estimation of the linear range, calibration function and limit of detection. as well as determination in real samples such as medication tablets were performed. According to the results. such a modified electrode appears to be a straightforward alternative to common glassy carbon or other modified electrodes. This thanks to the affinity of cysteic acid to the analyte, the low cost, the simplicity of the modification procedure and the reproducibility of the electrode surface.
引用
收藏
页码:772 / 778
页数:7
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