The NLRP3 Inflammasome Inhibitor OLT1177® Ameliorates Experimental Allergic Asthma in Mice

被引：1
|
作者：
Lunding, Lars P.
Skouras, Damaris B.
Vock, Christina
Dinarello, Charles A.
Wegmann, Michael
机构：
来源：
JOURNAL OF IMMUNOLOGY | 2022年 / 208卷 / 01期
关键词：
D O I：
10.4049/jimmunol.208.Supp.109.02
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
109.02
引用
收藏
页数：2
相关论文
共 50 条
  • [1] The NLRP3 inflammasome inhibitor, OLT1177®, ameliorates experimental allergic asthma in mice
    Lunding, Lars P.
    Skouras, Damaris B.
    Vock, Christina
    Dinarello, Charles A.
    Wegmann, Michael
    ALLERGY, 2022, 77 (03) : 1035 - +
  • [2] The inflammasome inhibitor OLT1177 improves experimental allergic asthma in mice
    Lunding, L.
    Skouras, D. B.
    Dinarello, C.
    Wegmann, M.
    ALLERGY, 2023, 78
  • [3] OLT1177 (Dapansutrile), a Selective NLRP3 Inflammasome Inhibitor, Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis
    Sanchez-Fernandez, Alba
    Skouras, Damaris B.
    Dinarello, Charles A.
    Lopez-Vales, Ruben
    FRONTIERS IN IMMUNOLOGY, 2019, 10
  • [4] The NLRP3 inhibitor, OLT1177 attenuates brain injury in experimental intracerebral hemorrhage
    Fang, Mei
    Xia, Fan
    Wang, Jiayan
    Wang, Chengyang
    Teng, Bang
    You, Shenglan
    Li, Manrui
    Chen, Xiameng
    Hu, Xin
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 131
  • [5] NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis
    Carlo Marchetti
    Benjamin Swartzwelter
    Marije I. Koenders
    Tania Azam
    Isak W. Tengesdal
    Nick Powers
    Dennis M. de Graaf
    Charles A. Dinarello
    Leo A. B. Joosten
    Arthritis Research & Therapy, 20
  • [6] NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis
    Marchetti, Carlo
    Swartzwelter, Benjamin
    Koenders, Marije I.
    Azam, Tania
    Tengesdal, Isak W.
    Powers, Nick
    de Graaf, Dennis M.
    Dinarello, Charles A.
    Joosten, Leo A. B.
    ARTHRITIS RESEARCH & THERAPY, 2018, 20
  • [7] THE HUMAN SAFE NLRP3 INFLAMMASOME INHIBITOR OLT1177 SUPPRESSES JOINT INFLAMMATION IN MURINE MODELS OF EXPERIMENTAL ARTHRITIS
    Marchetti, C.
    Swartzwelter, B.
    Koenders, I.
    Dinarello, C. A.
    Joosten, L. A.
    ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 89 - 89
  • [8] OLT1177 (Dapansutrile) Attenuates Retinal Neovascularization by Inhibiting NLRP3 Inflammasome Activation
    Wu, Peiqi
    Tang, Xiaoyu
    Cui, Kaixuan
    Wu, Peiqi
    Liang, Xiaoling
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2022, 63 (07)
  • [9] OLT1177 (Dapansutrile) Mitigates Retinal Neovascularization by Inhibiting NLRP3 Inflammasome Activation
    Wu, Peiqi
    Xu, Yue
    Liang, Xiaoling
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2024, 65 (07)
  • [10] NLRP3 Inflammasome Inhibitor OLT1177 Suppresses Onset of Inflammation in Mice with Dextran Sulfate Sodium-Induced Colitis
    Oizumi, Tomofumi
    Mayanagi, Taira
    Toya, Yosuke
    Sugai, Tamotsu
    Matsumoto, Takayuki
    Sobue, Kenji
    DIGESTIVE DISEASES AND SCIENCES, 2022, 67 (07) : 2912 - 2921
12345