The NLRP3 Inflammasome Inhibitor OLT1177® Ameliorates Experimental Allergic Asthma in Mice

被引：1
|
作者：
Lunding, Lars P.
Skouras, Damaris B.
Vock, Christina
Dinarello, Charles A.
Wegmann, Michael
机构：
来源：
JOURNAL OF IMMUNOLOGY | 2022年 / 208卷 / 01期
关键词：
D O I：
10.4049/jimmunol.208.Supp.109.02
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
109.02
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Preservation of Contractile Reserve and Diastolic Function by Inhibiting the NLRP3 Inflammasome with OLT1177(R) (Dapansutrile) in a Mouse Model of Severe Ischemic Cardiomyopathy Due to Non-Reperfused Anterior Wall Myocardial Infarction
    Aliaga, Joseph
    Bonaventura, Aldo
    Mezzaroma, Eleonora
    Dhakal, Yogesh
    Mauro, Adolfo Gabriele
    Abbate, Antonio
    Toldo, Stefano
    MOLECULES, 2021, 26 (12):
  • [42] Elevated expression of the NLRP3 inflammasome in neutrophilic asthma
    Simpson, Jodie L.
    Phipps, Simon
    Baines, Katherine J.
    Oreo, Kevin M.
    Gunawardhana, Lakshitha
    Gibson, Peter G.
    EUROPEAN RESPIRATORY JOURNAL, 2014, 43 (04) : 1067 - 1076
  • [43] NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer’s Disease
    Jun Yin
    Fanpeng Zhao
    Jeremy E. Chojnacki
    Jacob Fulp
    William L. Klein
    Shijun Zhang
    Xiongwei Zhu
    Molecular Neurobiology, 2018, 55 : 1977 - 1987
  • [44] NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer's Disease
    Yin, Jun
    Zhao, Fanpeng
    Chojnacki, Jeremy E.
    Fulp, Jacob
    Klein, William L.
    Zhang, Shijun
    Zhu, Xiongwei
    MOLECULAR NEUROBIOLOGY, 2018, 55 (03) : 1977 - 1987
  • [45] Forsythoside B ameliorates neuroinflammation via inhibiting NLRP3 inflammasome of glial cells in experimental autoimmune encephalomyelitis mice
    Wang, Yue
    Chen, Yongmin
    Lu, Jing
    Xiao, Qinqin
    Li, Ge
    Wang, Rong
    Chen, Rong
    Zhang, Da-Qi
    BRAIN RESEARCH BULLETIN, 2025, 220
  • [46] Brazilin is a natural product inhibitor of the NLRP3 inflammasome
    McMahon, Emily
    El-Sayed, Sherihan
    Green, Jack
    Hoyle, Christopher
    Fitzpatrick, Lorna
    V. Jones, Emma
    Corrie, Eve
    Kelly, Rebecca L.
    Challinor, Mairi
    Freeman, Sally
    Bryce, Richard A.
    Lawrence, Catherine B.
    Brough, David
    Kasher, Paul R.
    ISCIENCE, 2024, 27 (02)
  • [47] Yupingfeng San Inhibits NLRP3 Inflammasome to Attenuate the Inflammatory Response in Asthma Mice
    Liu, Xue
    Shen, Jiawen
    Fan, Danping
    Qiu, Xuemei
    Guo, Qingqing
    Zheng, Kang
    Luo, Hui
    Shu, Jun
    Lu, Cheng
    Zhang, Ge
    Lu, Aiping
    Ma, Chaoying
    He, Xiaojuan
    FRONTIERS IN PHARMACOLOGY, 2017, 8
  • [48] NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages
    Shi, Yuhua
    Lv, Qian
    Zheng, Mengjie
    Sun, Hongxiang
    Shi, Fushan
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 92
  • [49] Baicalin ameliorates atherosclerosis by inhibiting NLRP3 inflammasome in apolipoprotein E-deficient mice
    Zhao, Jingfei
    Wang, Zhengtang
    Yuan, Zhilu
    Lv, Shuzhen
    Su, Qingbo
    DIABETES & VASCULAR DISEASE RESEARCH, 2020, 17 (06):
  • [50] Inhibition of NLRP3 Inflammasome Ameliorates Cerebral Ischemia-Reperfusion Injury in Diabetic Mice
    Hong, Pu
    Li, Feng-Xian
    Gu, Ruo-Nan
    Fang, Ying-Ying
    Lai, Lu-Ying
    Wang, Yong-Wei
    Tao, Tao
    Xu, Shi-Yuan
    You, Zhi-Jian
    Zhang, Hong-Fei
    NEURAL PLASTICITY, 2018, 2018
12345