Oral immunotherapy with antigenicity-modified casein induces desensitization in cow's milk allergy

被引：6

作者：

Kawamoto, Norio ^{[1
]}

Kaneko, Hideo ^{[2
]}

Kawamoto, Minako ^{[1
]}

Ohnishi, Hidenori ^{[1
]}

Matsui, Eiko ^{[1
]}

Teramoto, Takahide ^{[1
]}

Kato, Zenichiro ^{[1
]}

Fukao, Toshiyuki ^{[1
]}

Ueno, Hiroshi M. ^{[3
]}

Nakano, Taku ^{[3
]}

Kondo, Naomi ^{[1
,4
]}

机构：

[1] Gifu Univ, Grad Sch Med, Dept Pediat, Yanagido 1-1, Gifu 5011194, Japan

[2] Nagara Med Ctr, Natl Hosp Org, Dept Clin Res, Gifu, Japan

[3] Bean Stalk Snow Co Ltd, Res & Dev Dept, Kawagoe, Saitama, Japan

[4] Heisei Coll Hlth Sci, Gifu, Japan

来源：

ALLERGY | 2020年 / 75卷 / 01期

关键词：

D O I：

10.1111/all.13965

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

It is relatively difficult to achieve clinical tolerance via OIT with cow's milk. In food allergy, immunotherapy using T-cell-tolerizing peptides is not well established. A novel antigenicity-modified form of cow's milk casein can be digested to avoid cross-reaction with IgE and retain the T-cell reaction.

引用

页码：197 / 200

页数：4

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