Oral immunotherapy with antigenicity-modified casein induces desensitization in cow's milk allergy

被引:6
|
作者
Kawamoto, Norio [1 ]
Kaneko, Hideo [2 ]
Kawamoto, Minako [1 ]
Ohnishi, Hidenori [1 ]
Matsui, Eiko [1 ]
Teramoto, Takahide [1 ]
Kato, Zenichiro [1 ]
Fukao, Toshiyuki [1 ]
Ueno, Hiroshi M. [3 ]
Nakano, Taku [3 ]
Kondo, Naomi [1 ,4 ]
机构
[1] Gifu Univ, Grad Sch Med, Dept Pediat, Yanagido 1-1, Gifu 5011194, Japan
[2] Nagara Med Ctr, Natl Hosp Org, Dept Clin Res, Gifu, Japan
[3] Bean Stalk Snow Co Ltd, Res & Dev Dept, Kawagoe, Saitama, Japan
[4] Heisei Coll Hlth Sci, Gifu, Japan
关键词
D O I
10.1111/all.13965
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
It is relatively difficult to achieve clinical tolerance via OIT with cow's milk. In food allergy, immunotherapy using T-cell-tolerizing peptides is not well established. A novel antigenicity-modified form of cow's milk casein can be digested to avoid cross-reaction with IgE and retain the T-cell reaction.
引用
收藏
页码:197 / 200
页数:4
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