Comparison of versions 1.0 and 1.5 of the UltraSensitive AMPLICOR HIV-1 MONITOR test for subjects with low viral load

被引：7
|
作者：
Jackson, JB
Piwowar-Manning, E
Johnson-Lewis, L
Bassett, R
Demeter, LM
Brambilla, D
机构：
[1] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21287 USA
[2] Harvard Univ, Sch Publ Hlth, SDAC, Boston, MA 02115 USA
[3] Univ Rochester, Med Ctr, Rochester, NY 14642 USA
[4] New England Res Inst, Watertown, MA 02472 USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2004年 / 42卷 / 06期
关键词：
D O I：
10.1128/JCM.42.6.2774-2776.2004
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We compared the performance of two UltraSensitive AMPLICOR HIV-1 MONITOR kits (version 1.5 [v1.5] versus v1.0) by retesting 404 plasma samples with low viral loads (<3,000 copies/ml) with both kits. With 292 samples that initially had <50 copies/ml by the v1.0 kit, the v1.5 assay was more sensitive than the v1.0 assay for samples with human immunodeficiency virus type 1 RNA near the 50-copy/ml cutoff (P = 0.0146). Median numbers of copies per milliliter were similar for 112 samples with 50 to 3,000 copies/ml with no difference in sensitivity with a 200-copy/ml cutoff.
引用
收藏
页码：2774 / 2776
页数：3
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