Comparison of versions 1.0 and 1.5 of the UltraSensitive AMPLICOR HIV-1 MONITOR test for subjects with low viral load

被引：7

作者：

Jackson, JB

Piwowar-Manning, E

Johnson-Lewis, L

Bassett, R

Demeter, LM

Brambilla, D

机构：

[1] Johns Hopkins Med Inst, Dept Pathol, Baltimore, MD 21287 USA

[2] Harvard Univ, Sch Publ Hlth, SDAC, Boston, MA 02115 USA

[3] Univ Rochester, Med Ctr, Rochester, NY 14642 USA

[4] New England Res Inst, Watertown, MA 02472 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2004年 / 42卷 / 06期

关键词：

D O I：

10.1128/JCM.42.6.2774-2776.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We compared the performance of two UltraSensitive AMPLICOR HIV-1 MONITOR kits (version 1.5 [v1.5] versus v1.0) by retesting 404 plasma samples with low viral loads (<3,000 copies/ml) with both kits. With 292 samples that initially had <50 copies/ml by the v1.0 kit, the v1.5 assay was more sensitive than the v1.0 assay for samples with human immunodeficiency virus type 1 RNA near the 50-copy/ml cutoff (P = 0.0146). Median numbers of copies per milliliter were similar for 112 samples with 50 to 3,000 copies/ml with no difference in sensitivity with a 200-copy/ml cutoff.

引用

页码：2774 / 2776

页数：3

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