Expression of Sox8, Sox9 and Sox10 in the developing valves and autonomic nerves of the embryonic heart

被引:46
|
作者
Montero, JA
Giron, B
Arrechedera, H
Cheng, YC
Scotting, P
Chimal-Monroy, J
Garcia-Porrero, JA
Hurle, JM [1 ]
机构
[1] Univ Cantabria, Fac Med, Dept Anat & Biol Celular, Santander 39011, Spain
[2] Univ Nottingham, Genet Inst, Nottingham NG7 2UH, England
[3] Cent Univ Venezuela, Fac Med, Inst Trop Med, Caracas, Venezuela
[4] Univ Nottingham, Inst Genet, Nottingham NG7 2UH, England
关键词
Sox8; Sox9; Sox10; embryonic heart; chick embryo; aggrecan;
D O I
10.1016/S0925-4773(02)00249-6
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We describe the expression pattern of Sox8, Sox9 and Sox10 during the development of the chick embryo heart. These Sox genes constitute the group E of the large Sox family of transcription factors. We show that the expression of Sox8, Sox9 and Sox10 in the developing heart correlates with heart septation and with the differentiation of the connective tissue of the valve leaflets. Sox10 appears also as a specific marker of developing heart nerves. These findings fit with the occurrence of morphological and functional anomalies of the heart reported in humans deficient for Sox9 and Sox10. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:199 / 202
页数:4
相关论文
共 50 条
  • [21] Stability and Prognostic Value of Slug, Sox9 and Sox10 Expression in Breast Cancers Treated with Neoadjuvant Chemotherapy
    Riemenschnitter, C.
    Teleki, I.
    Tischler, V.
    Guo, W.
    Varga, Z.
    MODERN PATHOLOGY, 2013, 26 : 65A - 65A
  • [22] Stability and prognostic value of Slug, Sox9 and Sox10 expression in breast cancers treated with neoadjuvant chemotherapy
    Riemenschnitter, Cosima
    Teleki, Ivett
    Tischler, Verena
    Guo, Wenjun
    Varga, Zsuzsanna
    SPRINGERPLUS, 2013, 2
  • [23] Impaired autonomic control of the heart by SOX10 mutation
    Korsch, E
    Steinkuhle, J
    Massin, M
    Lyonnet, S
    Touraine, RL
    EUROPEAN JOURNAL OF PEDIATRICS, 2001, 160 (01) : 68 - 69
  • [24] Impaired autonomic control of the heart by SOX10 mutation
    Eckhard Korsch
    Jutta Steinkuhle
    Martial Massin
    Stanislas Lyonnet
    Renaud L. Touraine
    European Journal of Pediatrics, 2001, 160 : 68 - 69
  • [25] Sox9 and Sox10 influence survival and migration of oligodendrocyte precursors in the spinal cord by regulating PDGF receptor α expression
    Finzsch, Markus
    Stolt, C. Claus
    Lommes, Petra
    Wegner, Michael
    DEVELOPMENT, 2008, 135 (04): : 637 - 646
  • [26] Sox2 and sox10 expression patterning in melanoma
    Wan, M. T.
    Kakavand, H.
    Mihm, M. C.
    Scolyer, R. A.
    Thompson, J. T.
    Murphy, G. F.
    Lin, J. Y.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2014, 134 : S129 - S129
  • [27] The transcription factors SOX9 and SOX10 are vitiligo autoantigens in autoimmune polyendocrine syndrome type I
    Hedstrand, H
    Ekwall, O
    Olsson, MJ
    Landgren, E
    Kemp, EH
    Weetman, AP
    Perheentupa, J
    Husebye, E
    Gustafsson, J
    Betterle, C
    Kämpe, O
    Rorsman, F
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (38) : 35390 - 35395
  • [28] The group E Sox genes Sox8 and Sox9 are regulated by Notch signaling and are required for Muller glial cell development in mouse retina
    Muto, Akihiko
    Iida, Atsumi
    Satoh, Shinya
    Watanabe, Sumiko
    EXPERIMENTAL EYE RESEARCH, 2009, 89 (04) : 549 - 558
  • [29] Cloning and Expression of Sox2 and Sox9 in Embryonic and Gonadal Development of Lutraria sieboldii
    Lu, Min
    Xing, Zenghou
    Zhou, Yurui
    Xu, Youhou
    Peng, Huijing
    Zou, Jie
    Dan, Solomon Felix
    She, Zhicai
    Wang, Pengliang
    Liu, Jinfeng
    Qin, Shaomin
    Yang, Jialin
    Zhu, Peng
    FISHES, 2022, 7 (06)
  • [30] Expression of Sox5, Sox8 and Sox9 Genes in Golden Pompano Trachinotus ovatus (Linnaeus 1758) Larvae During Ontogeny and in Response to Water Temperature
    Ma, Zhenhua
    Fu, Mingjun
    Peng, Xiaoyu
    Qin, Jian G.
    ISRAELI JOURNAL OF AQUACULTURE-BAMIDGEH, 2017, 69