Inhibition of the vascular endothelial growth factor (VEGF) receptor (KDR/Flk-1) decreases alveolarization and alters vascular growth and structure in the developing rat lung

被引:0
|
作者
Jakkula, M
Le Cras, TD
Gebb, SA
Hirth, KP
Tuder, RM
Voelkel, NF
Abman, SH
机构
[1] Univ Colorado, Sch Med, Pediat Heart Lung Ctr, Denver, CO 80202 USA
[2] Sugen Inc, San Francisco, CA USA
[3] Univ Colorado, Sch Med, Denver, CO 80202 USA
关键词
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
416
引用
收藏
页码:71A / 71A
页数:1
相关论文
共 50 条
  • [21] Expression of Vascular Endothelial Growth Factor and Flk-1 in Developing and Glucocorticoid-Treated Mouse Lung
    Abhay J Bhatt
    Sanjiv B Amin
    Patricia R Chess
    Richard H Watkins
    William M Maniscalco
    Pediatric Research, 2000, 47 : 606 - 613
  • [22] Immunohistochemical detection of vascular endothelial growth factor (VEGF) and VEGF receptors Flt-1 and KDR/Flk-1 in the cochlea of guinea pigs
    Michel, O
    Hess, A
    Bloch, W
    Schmidt, A
    Stennert, E
    Addicks, K
    HEARING RESEARCH, 2001, 155 (1-2) : 175 - 180
  • [23] Expression of vascular endothelial growth factor (VEGF) and VEGF receptor Flk-1 in benign, premalignant, and malignant prostate tissue
    Köllermann, J
    Helpap, B
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2001, 116 (01) : 115 - 121
  • [24] Systemic activation of the vascular endothelial growth factor receptor KDR/flk-1 selectively triggers endothelial cells with an angiogenic phenotype
    Ortega, N
    Jonca, F
    Vincent, S
    Favard, C
    Ruchoux, MM
    Plouet, J
    AMERICAN JOURNAL OF PATHOLOGY, 1997, 151 (05): : 1215 - 1224
  • [25] Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors
    McCabe, CJ
    Boelaert, K
    Tannahill, LA
    Heaney, AP
    Stratford, AL
    Khaira, JS
    Hussain, S
    Sheppard, MC
    Franklyn, JA
    Gittoes, NJL
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (09): : 4238 - 4244
  • [26] HoxB5 transcriptionally regulates the vascular endothelial growth factor receptor KDR/flk-1 in vitro and in vivo
    Wu, YX
    Patterson, C
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2002, 22 (05) : A6 - A6
  • [27] Regulation of vascular endothelial growth factor receptor-2 (Flk-1) expression in vascular endothelial cells
    Pepper, MS
    Mandriota, SJ
    EXPERIMENTAL CELL RESEARCH, 1998, 241 (02) : 414 - 425
  • [28] Immunohistochemical detection of vascular endothelial growth factor (VEGF) and VEGF-receptors Flt-1 and KDR/Flk-1 in the vestibule of guinea pigs
    Hess, A
    Bloch, W
    Wittekindt, C
    Siodladczek, J
    Addicks, K
    Michel, O
    NEUROSCIENCE LETTERS, 2000, 280 (02) : 147 - 150
  • [29] Hypoxia inducible factor 1 alpha, vascular endothelial growth factor and Kdr/Flk-1 overexpression in ischemic colitis
    Okuda, T
    Azuma, T
    Satomi, S
    Ohtani, M
    Masaki, R
    Ito, Y
    Suto, H
    Yamazaki, Y
    Ito, S
    GASTROENTEROLOGY, 2005, 128 (04) : A658 - A658
  • [30] Analysis of vascular endothelial growth factor (VEGF) and a receptor subtype (KDR/flk-1) in the liver of rats exposed to riddelliine: a potential role in the development of hemangiosarcoma
    Moyer, C
    Allen, D
    Basabe, A
    Maronpot, RR
    Nyska, A
    EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, 2004, 55 (06) : 455 - 465