Inhibition of the vascular endothelial growth factor (VEGF) receptor (KDR/Flk-1) decreases alveolarization and alters vascular growth and structure in the developing rat lung

被引:0
|
作者
Jakkula, M
Le Cras, TD
Gebb, SA
Hirth, KP
Tuder, RM
Voelkel, NF
Abman, SH
机构
[1] Univ Colorado, Sch Med, Pediat Heart Lung Ctr, Denver, CO 80202 USA
[2] Sugen Inc, San Francisco, CA USA
[3] Univ Colorado, Sch Med, Denver, CO 80202 USA
关键词
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
416
引用
收藏
页码:71A / 71A
页数:1
相关论文
共 50 条
  • [11] Inhibition of vascular endothelial growth factor and receptor, KDR/Flk-1 interaction attenuates the murine liver fibrosis development.
    Yoshiji, H
    Kuriyama, S
    Yoshii, J
    Ikenaka, Y
    Noguchi, R
    Yanase, K
    Namisaki, T
    Tsujinoue, H
    Fukui, H
    HEPATOLOGY, 2002, 36 (04) : 315A - 315A
  • [12] CLOTTING AND FUNCTIONAL-ANALYSIS OF THE PROMOTER FOR KDR/FLK-1, A RECEPTOR FOR VASCULAR ENDOTHELIAL GROWTH-FACTOR
    PATTERSON, C
    PARRELLA, MA
    HSIEH, CM
    YOSHIZUMI, M
    LEE, ME
    HABER, E
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (39) : 23111 - 23118
  • [13] Expression of vascular endothelial growth factor and its receptor (KDR/flk-1) mRNA in experimental choroidal neovascularization
    Wada, M
    Ogata, N
    Otsuji, T
    Uyama, M
    CURRENT EYE RESEARCH, 1999, 18 (03) : 203 - 213
  • [14] Vascular endothelial growth factor and its receptor, Flk-1/KDR, are cytoprotective in the extravascular compartment of the ovarian follicle
    Greenaway, J
    Connor, K
    Pedersen, HG
    Coomber, BL
    Lamarre, J
    Petrik, J
    ENDOCRINOLOGY, 2004, 145 (06) : 2896 - 2905
  • [15] Homologous up-regulation of KDR/Flk-1 receptor expression by vascular endothelial growth factor in vitro
    Shen, BQ
    Lee, DY
    Gerber, HP
    Keyt, BA
    Ferrara, N
    Zioncheck, TF
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (45) : 29979 - 29985
  • [17] Expression of vascular endothelial growth factor (VEGF) and its receptor (flk-1) increase during lung development.
    Amin, SB
    Watkins, RH
    Swantz, RJ
    Staversky, RJ
    Maniscalco, WM
    PEDIATRIC RESEARCH, 1996, 39 (04) : 323 - 323
  • [18] Design of a variant of vascular endothelial growth factor-A (VEGF-A) antagonizing KDR/Flk-1 and Flt-1
    Leenders, W
    Lubsen, N
    van Altena, M
    Clauss, M
    Deckers, M
    Löwik, C
    Breier, G
    Ruiter, D
    de Waal, R
    LABORATORY INVESTIGATION, 2002, 82 (04) : 473 - 481
  • [19] Flt-1 but not KDR/Flk-1 tyrosine kinase is a receptor for placenta growth factor, which is related to vascular endothelial growth factor
    Sawano, A
    Takahashi, T
    Yamaguchi, S
    Aonuma, M
    Shibuya, M
    CELL GROWTH & DIFFERENTIATION, 1996, 7 (02): : 213 - 221
  • [20] Expression of vascular endothelial growth factor and Flk-1 in developing and glucocorticoid-treated mouse lung
    Bhatt, AJ
    Amin, SB
    Chess, PR
    Watkins, RH
    Maniscalco, WM
    PEDIATRIC RESEARCH, 2000, 47 (05) : 606 - 613