Dietary short-chain fatty acids protect against type 1 diabetes

被引:56
|
作者
Wen, Li [1 ]
Wong, F. Susan [2 ]
机构
[1] Yale Univ, Sch Med, Dept Internal Med, Sect Endocrinol, New Haven, CT 06510 USA
[2] Cardiff Univ, Div Infect & Immun, Sch Med, Cardiff, S Glam, Wales
基金
英国医学研究理事会;
关键词
T-CELLS; ANTIGEN;
D O I
10.1038/ni.3730
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The short-chain fatty acids (SCFAs) acetate and butyrate, which are released from specialized diets by gut microbes, protect non-obese diabetic (NOD) mice against insulitis and slow the progression of diabetes.
引用
收藏
页码:484 / 486
页数:4
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