Key Rep-Proteins Necessary for the Adeno-Associated Virus Production by Transient Transfection in HEK293 Cells in Suspension and Serum-Free Medium

被引:0
|
作者
Chahal, Parminder [1 ]
Elahi, Mehdy [1 ]
O'Neil, Patrick. [1 ]
Venne, Marie-Helene. [1 ]
Nazemi-Moghaddam, Nazila [1 ]
Gilbert, Renald [1 ]
机构
[1] Natl Res Council Canada, Human Hlth Therapeut Portfolio, Montreal, PQ, Canada
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
713
引用
收藏
页码:328 / 328
页数:1
相关论文
共 50 条
  • [41] Production of rVSV-ZEBOV in serum-free suspension culture of HEK 293SF cells
    Gelinas, Jean-Francois
    Azizi, Hiva
    Kiesslich, Sascha
    Lanthier, Stephane
    Perdersen, Jannie
    Chahal, Parminder S.
    Ansorge, Sven
    Kobinger, Gary
    Gilbert, Renald
    Kamen, Amine A.
    VACCINE, 2019, 37 (44) : 6624 - 6632
  • [42] Transient Production of Recombinant Adeno-Associated Virus (AAV) Vectors for Gene Therapy Applications Using Suspension-Adapted HEK 293 Cells in Orbital Shaken Bioreactors
    Blessing, Daniel R.
    Montavon, Monique
    de Jesus, Maria
    Baldi, Lucia
    Schneider, Bernard
    Wurm, Florian M.
    Deglon, Nicole
    MOLECULAR THERAPY, 2015, 23 : S184 - S185
  • [43] Robust Lentivirus and Adeno-Associated Virus Production Through the Optimization of Key Transient Transfection Experimental Variables
    Ludtke, James
    Storck, Austin
    Juckem, Laura
    MOLECULAR THERAPY, 2020, 28 (04) : 209 - 209
  • [44] Development of a Serum-Free Suspension HEK293 Cell Line for AAV Production with High Yield and Low Encapsidated DNA Impurities
    Yang, Hairui
    MOLECULAR THERAPY, 2024, 32 (04) : 511 - 511
  • [45] Characterizing Glycosylation of Adeno-Associated Virus Serotype 9 Capsid Proteins Generated from HEK293 Cells through Glycopeptide Mapping and Released Glycan Analysis
    Zhou, Yu
    Priya, Sonal
    Ong, Joseph Y.
    MICROORGANISMS, 2024, 12 (05)
  • [46] Significant Differences in Capsid Properties and Potency Between Adeno-Associated Virus Vectors Produced in Sf9 and HEK293 Cells
    Giles, April
    Lock, Martin
    Chen, Shu-Jen
    Turner, Kevin
    Wesolowski, Gregg
    Prongay, Andrew
    Petkov, Boris N.
    Olagbegi, Kanyin
    Yan, Hanying
    Wilson, James M.
    HUMAN GENE THERAPY, 2023, 34 (19-20) : 1003 - 1021
  • [47] Production of Recombinant Adeno-associated Virus Vectors Using Suspension HEK293 Cells and Continuous Harvest of Vector From the Culture Media for GMP FIX and FLT1 Clinical Vector
    Grieger, Joshua C.
    Soltys, Stephen M.
    Samulski, Richard Jude
    MOLECULAR THERAPY, 2016, 24 (02) : 287 - 297
  • [48] Sodium Chloride Enhances Recombinant Adeno-Associated Virus Production in a Serum-Free Suspension Manufacturing Platform Using the Herpes Simplex Virus System
    Adamson-Small, Laura
    Potter, Mark
    Byrne, Barry J.
    Clement, Nathalie
    HUMAN GENE THERAPY METHODS, 2017, 28 (01) : 1 - 14
  • [49] Serum-Free Suspension Adaptation of HEK-293T Cells: Basis for Large-Scale Biopharmaceutical Production
    Oliveira Lomba, Ana Luiza
    Covas, Dimas Tadeu
    Tirapelle, Mariane Cariati
    Picanco-Castro, Virginia
    Biaggio, Rafael Tage
    Swiech, Kamilla
    Abreu-Neto, Mario Soares
    Mizukami, Amanda
    BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY, 2021, 64
  • [50] Low-glutamine fed-batch cultures of 293-HEK serum-free suspension cells for adenovirus production
    Lee, YY
    Yap, MGS
    Hu, WS
    Wong, KTK
    BIOTECHNOLOGY PROGRESS, 2003, 19 (02) : 501 - 509