Key Rep-Proteins Necessary for the Adeno-Associated Virus Production by Transient Transfection in HEK293 Cells in Suspension and Serum-Free Medium

被引：0
|
作者：
Chahal, Parminder [1 ]
Elahi, Mehdy [1 ]
O'Neil, Patrick. [1 ]
Venne, Marie-Helene. [1 ]
Nazemi-Moghaddam, Nazila [1 ]
Gilbert, Renald [1 ]
机构：
[1] Natl Res Council Canada, Human Hlth Therapeut Portfolio, Montreal, PQ, Canada
来源：
MOLECULAR THERAPY | 2018年 / 26卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
713
引用
收藏
页码：328 / 328
页数：1
相关论文
共 50 条
  • [1] Towards Large-Scale Manufacturing of Adeno-Associated Virus by Transient Transfection of HEK293 Suspension Cells in a Stirred Tank Bioreactor Using Serum-Free Medium
    Chahal, Parminder
    Schulze, Erica Alessandra
    Bernier, Alice
    Lanthier, Stephane
    Coulombe, Nathalie
    Kamen, Amine
    Gilbert, Renald
    MOLECULAR THERAPY, 2016, 24 : S117 - S118
  • [2] Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells
    Durocher, Yves
    Pham, Phuong Lan
    St-Laurent, Gilles
    Jacob, Danielle
    Cass, Brian
    Chahal, Parminder
    Lau, Cara J.
    Nalbantoglu, Josphine
    Kamen, Amine
    JOURNAL OF VIROLOGICAL METHODS, 2007, 144 (1-2) : 32 - 40
  • [3] Production of adeno-associated virus (AAV) serotypes by transient transfection of HEK293 cell suspension cultures for gene delivery
    Chahal, Parminder Singh
    Schulze, Erica
    Tran, Rosa
    Montes, Johnny
    Kamen, Amine A.
    JOURNAL OF VIROLOGICAL METHODS, 2014, 196 : 163 - 173
  • [4] Establishment of a Clonal, Serum-Free, Suspension-Adapted HEK293 Cell Line for the Manufacturing of Adeno-Associated Virus Vectors
    Campbell, Marguerite
    Geosits, Kelly
    Ercolino, Matthew
    Burton, Thomas J.
    Ngan Trinh
    Umaer, Khan
    Tummala, Srivanya
    Sacks, Amy
    Tomkowicz, Brian
    MOLECULAR THERAPY, 2023, 31 (04) : 494 - 494
  • [5] Mechanistic model for production of recombinant adeno-associated virus via triple transfection of HEK293 cells
    Nguyen, Tam N. T.
    Sha, Sha
    Hong, Moo Sun
    Maloney, Andrew J.
    Barone, Paul W.
    Neufeld, Caleb
    Wolfrum, Jacqueline
    Springs, Stacy L.
    Sinskey, Anthony J.
    Braatz, Richard D.
    MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021, 21 : 642 - 655
  • [6] Process modeling of recombinant adeno-associated virus production in HEK293 cells
    Joiner, Jordan
    Huang, Zhuangrong
    McHugh, Kyle
    Stebbins, Matthew
    Aron, Kathryn
    Borys, Michael
    Khetan, Anurag
    CURRENT OPINION IN CHEMICAL ENGINEERING, 2022, 36
  • [7] The Unveiled Novel regulator of Adeno-associated virus production in HEK293 cells
    Yan, Junyu
    Li, Ziqian
    Shu, Yue
    Chen, Hui
    Wang, Tianxingzi
    Li, Xin
    Zhang, Yuhang
    Li, Lili
    Zhang, Yuntao
    GENE, 2025, 938
  • [8] A feasibility study of different commercially available serum-free mediums to enhance lentivirus and adeno-associated virus production in HEK 293 suspension cells
    Gizem Celebi Torabfam
    Abuzer Alp Yetisgin
    Cem Erdem
    Aziz Cayli
    Ozlem Kutlu
    Sibel Cetinel
    Cytotechnology, 2022, 74 : 635 - 655
  • [9] A feasibility study of different commercially available serum-free mediums to enhance lentivirus and adeno-associated virus production in HEK 293 suspension cells
    Torabfam, Gizem Celebi
    Yetisgin, Abuzer Alp
    Erdem, Cem
    Cayli, Aziz
    Kutlu, Ozlem
    Cetinel, Sibel
    CYTOTECHNOLOGY, 2022, 74 (06) : 635 - 655
  • [10] Scalable platform for production of recombinant adeno-associated viral vectors in suspension HEK293 cells
    Chippendale, T.
    Silvano, M.
    Krakowiak, J.
    Hassall, A.
    Wong, A.
    Tam, L.
    Liu, Q.
    Payne, T.
    HUMAN GENE THERAPY, 2019, 30 (08) : A22 - A22
12345